Sealy Center of Aging, The University of Texas Medical Branch, Galveston, TX, USA.
Preventive Medicine and Population Health, The University of Texas Medical Branch, Galveston, TX, USA.
Ethn Health. 2022 Nov;27(8):1915-1931. doi: 10.1080/13557858.2021.2002271. Epub 2021 Nov 22.
Arthritis is a common chronic condition in the ageing population. Its impact on physical function varies according to sociodemographic and race/ethnic factors. The study objective was to examine the impact of arthritis on physical function and disability among non-disabled older Mexican Americans over time.
A 23-year prospective cohort study of 2230 Mexican Americans aged 65 years and older from the Hispanic Established Population for the Epidemiologic Study of the Elderly (1993/94-2016). The independent variable was self-reported physician-diagnosed arthritis, and the outcomes included Activities of Daily Living (ADL), Instrumental Activities of Daily Living (IADL), mobility, Short Physical Performance Battery (SPPB), and handgrip strength. Covariates were sociodemographic, medical conditions, body mass index, depressive symptoms, and cognitive function. General linear mixed models were performed to estimate the change in SPPB and muscle strength. General Equation Estimation models estimated the odds ratios (OR) of becoming ADL- or IADL- or mobility - disabled as a function of arthritis. All variables were used as time-varying except for sex, education, and nativity.
Overall, participants with arthritis had higher odds ratio (OR) of any ADL [OR = 1.35, 95% Confidence Interval (CI) = 1.09-1.68] and mobility (OR = 1.34, 95% CI = 1.18-1.52) disability over time than those without arthritis, after controlling for all covariates. Women, but not men, reporting arthritis had increased risk for ADL and mobility disability. The total SPPB score declined 0.18 points per year among those with arthritis than those without arthritis, after controlling for all covariates (-value < .010).
Our study demonstrates the independent effect of arthritis in increasing ADL and mobility disability and decreased physical function in older Mexican Americans over 23-years of follow-up.
关节炎是老年人群中常见的慢性疾病。其对身体功能的影响因社会人口学和种族/民族因素而异。本研究的目的是随着时间的推移，检查关节炎对无残疾的老年墨西哥裔美国人身体功能和残疾的影响。
这是一项对来自西班牙裔美国人老龄化人口的流行病学研究（1993/94-2016 年）的 2230 名年龄在 65 岁及以上的墨西哥裔美国人进行的 23 年前瞻性队列研究。自变量是自我报告的医生诊断的关节炎，结局包括日常生活活动（ADL）、工具性日常生活活动（IADL）、活动能力、简短身体表现测试（SPPB）和手握力。协变量为社会人口学、医疗状况、体重指数、抑郁症状和认知功能。采用一般线性混合模型来估计 SPPB 和肌肉力量的变化。一般方程估计模型估计了关节炎作为 ADL 或 IADL 或活动能力障碍的发生的比值比（OR）。除了性别、教育程度和出生地之外，所有变量均作为时变变量使用。
总体而言，患有关节炎的参与者发生任何 ADL[比值比（OR）=1.35，95%置信区间（CI）=1.09-1.68]和活动能力（OR=1.34，95%CI=1.18-1.52）残疾的可能性高于无关节炎的参与者，在控制所有协变量后。报告有关节炎的女性，而不是男性，ADL 和活动能力残疾的风险增加。在控制所有协变量后，患有关节炎的人的总 SPPB 评分每年下降 0.18 分，而没有关节炎的人则下降 0.18 分（-值<.010）。
我们的研究表明，关节炎对 23 年随访期间老年墨西哥裔美国人的 ADL 和活动能力残疾以及身体功能下降有独立影响。
