免疫功能正常患者的巨细胞病毒相关性胃溃疡和胃十二指肠炎症：病例报告及文献综述

CMV-Related Gastric Ulcer and Gastroduodenitis in an Immunocompetent Patient: A Case Report and Literature Review.

作者信息

Beany Andrawus, Rainis Tova

机构信息

Division of Gastroenterology, Bnai Zion Medical Center, Haifa, Israel.

The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel.

出版信息

Case Rep Gastrointest Med. 2021 Nov 12;2021:3513223. doi: 10.1155/2021/3513223. eCollection 2021.

DOI:10.1155/2021/3513223

PMID:34804617

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8604585/

Abstract

BACKGROUND

Cytomegalovirus (CMV)- related gastroduodenal infection is rare in immunocompetent hosts, and although it is considered a self-limiting condition in most cases, there is scarce literature to assert its management. . We report a case of a 66-year-old immunocompetent male patient diagnosed with a giant gastric ulcer caused by CMV infection. The ulcer manifested as refractory vomiting and melena. Rapid and full resolution was observed on proton-pump inhibitor (PPI) monotherapy.

CONCLUSION

Gastric CMV infection might mimic an advanced gastric tumor in individuals with an intact immune system. The condition is rare, and the diagnosis is challenging and oftentimes overlooked. However, a rapid resolution has been documented in all cases, even without antiviral therapy.

摘要

背景

巨细胞病毒（CMV）相关的胃十二指肠感染在免疫功能正常的宿主中较为罕见，尽管在大多数情况下被认为是一种自限性疾病，但关于其治疗的文献却很少。我们报告一例66岁免疫功能正常的男性患者，诊断为CMV感染引起的巨大胃溃疡。该溃疡表现为难治性呕吐和黑便。质子泵抑制剂（PPI）单药治疗后观察到迅速且完全缓解。