中年人群中婚姻关系与多种疾病共存的关系:一项横跨美国、英国、欧洲和中国的纵向研究。
Association between marital relationship and multimorbidity in middle-aged adults: a longitudinal study across the US, UK, Europe, and China.
机构信息
Second Affiliated Hospital and School of Public Health, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Academy for Data Science and Global Health, Kathmandu, Nepal.
出版信息
Maturitas. 2022 Jan;155:32-39. doi: 10.1016/j.maturitas.2021.09.011. Epub 2021 Oct 3.
BACKGROUND
Marital relationship plays an important role in health and wellbeing. However, how marriage is associated with multimorbidity (the co-occurrence of two or more chronic conditions) has not been comprehensively investigated. We aimed to assess the association between marriage and multimorbidity in middle-aged adults.
METHODS
We used nationally representative data on 23641 adults aged 50-60 years who participated in four longitudinal studies in the US, UK, Europe, and China (Health and Retirement Study, English Longitudinal Study on Ageing, Survey of Health, Ageing and Retirement in Europe, and China Health and Retirement Longitudinal Study). Respondents were followed up in 2010-11 (baseline), 2012-13, and 2014-15. We used generalized estimating equations to evaluate the associations between marital status (married/partnered or non-married [separated/devoiced/widowed/never married]), marriage duration and multimorbidity, adjusting for socioeconomic and lifestyle factors.
RESULTS
Over 4-year follow-up, 24% (n=5699) of respondents experienced separation, divorce, widowhood, or never-married status, and approximately 43% (n=10228) of respondents reported multimorbidity. Those who were not married had a higher odds of multimorbidity (age-, sex- and region-adjusted odds ratio 1.19; 95% confidence interval 1.14 to 1.25). Those who had been married for 21-30 years had a lower odds of experiencing multimorbidity than those married for less than 10 years. The associations remained robust after adjusting for socioeconomic and lifestyle factors.
CONCLUSIONS
Marital relationship (status and length) was associated with multimorbidity in middle-aged adults, highlighting the role of marital relationship in shaping the trajectory of health and wellbeing across the life course. These findings provide insight for the prevention and management of chronic disease and multimorbidity.
背景
婚姻关系对健康和幸福起着重要作用。然而,婚姻与多种疾病(两种或多种慢性疾病同时存在)的关系尚未得到全面研究。本研究旨在评估中年人群中婚姻与多种疾病的关系。
方法
我们使用了美国、英国、欧洲和中国的四项纵向研究中 23641 名 50-60 岁成年人的全国代表性数据(健康与退休研究、英国老龄化纵向研究、欧洲健康、老龄化和退休调查、中国健康与退休纵向研究)。受访者在 2010-11 年(基线)、2012-13 年和 2014-15 年进行了随访。我们使用广义估计方程来评估婚姻状况(已婚/有伴侣或未婚[分居/离异/丧偶/未婚])、婚姻持续时间与多种疾病之间的关联,同时调整了社会经济和生活方式因素。
结果
在 4 年的随访期间,24%(n=5699)的受访者经历了分居、离婚、丧偶或未婚状态,约 43%(n=10228)的受访者报告了多种疾病。未婚者发生多种疾病的可能性更高(年龄、性别和地区调整后的优势比 1.19;95%置信区间 1.14 至 1.25)。与结婚不到 10 年的人相比,结婚 21-30 年的人发生多种疾病的可能性较低。在调整了社会经济和生活方式因素后,这些关联仍然成立。
结论
婚姻关系(状况和持续时间)与中年人群的多种疾病有关,这突出了婚姻关系在塑造整个生命历程中健康和幸福轨迹方面的作用。这些发现为慢性疾病和多种疾病的预防和管理提供了参考。