埃塞俄比亚东北部一家转诊医院 2 型糖尿病患者血脂异常的患病率及危险因素。

Prevalence and Risk Factors of Dyslipidemia among Type 2 Diabetes Patients at a Referral Hospital, North Eastern Ethiopia.

机构信息

Department of Nursing, College of Health Sciences, Debre Berhan University, Debre Berhan, Ethiopia.

Department of Psychiatry, College of Health Sciences, Debre Berhan University, Debre Berhan, Ethiopia.

出版信息

Ethiop J Health Sci. 2021 Nov;31(6):1267-1276. doi: 10.4314/ejhs.v31i6.23.

Abstract

BACKGROUND

The prevalence of diabetes and its associated complications rising in Ethiopia ranged from 2.0%-6.5%, the primary cause of morbidity and mortality with consequential economic impact. This study aimed to assess the prevalence and risk factors of dyslipidemia among diabetes follow-up patients.

METHODS

Institution-based cross-sectional study was conducted at Debre Berhan Referral Hospital from January to March 2020 in 347 Adult type 2 diabetes follow-up patients using a convenient sampling technique. Data were collected by interviews and entered using Epi-data 4.2 and analyzed using SPSS version 25. Factors having a p-value < 0.25 in the bi-variable logistic regression model were entered into a multivariable logistic regression model. Statistical Significance was declared at a p-value ≤ of 0.05.

RESULTS

The prevalence of dyslipidemia among type 2 diabetes patients in this study was 59 %. Significantly associated variables were being female [AOR 2.6 (95% CI 1.2-3.2), P = 0.011], smoking history [AOR 4.1 (95% CI 2-6.8), P = 0.001], Being overweight [AOR 3.5 (95% CI 1.6-7.8), P = 0.002], Being obese [AOR 4.8 (95% CI 1.7-13), P = 0.002].

CONCLUSION

Prevalence of dyslipidemia was high among diabetic patients, which accounts for 59%. Being female, smoking history, being overweight, and being obese were determinants of dyslipidemia. Patients with poor glycemic control need additional lipid-lowering therapies to prevent secondary Atherosclerotic vascular complications.

摘要

背景

在埃塞俄比亚,糖尿病及其相关并发症的患病率从 2.0%-6.5%不等,是发病率和死亡率的主要原因,并带来了相应的经济影响。本研究旨在评估糖尿病随访患者中血脂异常的患病率和危险因素。

方法

2020 年 1 月至 3 月,在德布雷伯汉转诊医院进行了一项基于机构的横断面研究,使用便利抽样技术对 347 名成年 2 型糖尿病随访患者进行研究。通过访谈收集数据,并使用 Epi-data 4.2 录入,使用 SPSS 25 版本进行分析。在双变量逻辑回归模型中 p 值<0.25 的因素被纳入多变量逻辑回归模型。统计显著性以 p 值≤0.05 为标准。

结果

本研究中 2 型糖尿病患者血脂异常的患病率为 59%。具有显著相关性的变量为女性[OR 2.6(95%CI 1.2-3.2),P=0.011]、吸烟史[OR 4.1(95%CI 2-6.8),P=0.001]、超重[OR 3.5(95%CI 1.6-7.8),P=0.002]、肥胖[OR 4.8(95%CI 1.7-13),P=0.002]。

结论

糖尿病患者血脂异常的患病率较高,占 59%。女性、吸烟史、超重和肥胖是血脂异常的决定因素。血糖控制不佳的患者需要额外的降脂治疗来预防继发性动脉粥样硬化血管并发症。

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