Department of Surgery, Division of Vascular Surgery, King Saud University, College of Medicine, Riyadh, Saudi Arabia.
Braz J Cardiovasc Surg. 2022 May 23;37(3):385-393. doi: 10.21470/1678-9741-2020-0611.
Tuberculous aortic aneurysm (TBAA) is an exceedingly rare but severe manifestation of tuberculosis, with a high risk of sudden rupture of the aorta in absence of medical or surgical intervention. This review aimed to provide a detailed understanding of TBAA, including its associated complications, affected population, treatment measures, and outcomes.
Case studies and relevant research articles were analyzed to understand the recent advances in medical scientific knowledge on TBAA. Recent clinical case reports on TBAA were searched from the year 2010 to 2020.
Case reports indicated a higher prevalence of TBAA in the male population. The most affected age group was 15 to 79 years. The most common treatment for TBAA included surgery followed by antituberculous medication. The case reports discussed in this review reflected open surgery, endovascular repair, coil embolization, laparotomy, aortic valve and root replacement as some of the surgical procedures used depending on the complication and type of aneurysm. The treatment outcome was considered effective in most cases.
Postoperative chemotherapy and medications reduce the risk of severity. Early diagnosis of TBAA is imperative, followed by surgical resection and postoperative antituberculous medication with careful follow-up to prevent relapse.
结核性主动脉瘤(TBAA)是一种极为罕见但严重的结核病表现,如果不进行医学或手术干预,主动脉有突然破裂的高风险。本综述旨在详细了解 TBAA,包括其相关并发症、受影响人群、治疗措施和结果。
分析病例研究和相关研究文章,以了解 TBAA 在医学科学知识方面的最新进展。从 2010 年到 2020 年,搜索了有关 TBAA 的最近临床病例报告。
病例报告表明,TBAA 在男性人群中的患病率较高。受影响的最常见年龄组为 15 至 79 岁。TBAA 的最常见治疗方法包括手术加抗结核药物治疗。本综述中讨论的病例报告反映了开放性手术、血管内修复、线圈栓塞、剖腹手术、主动脉瓣和根部置换等一些手术程序的使用,具体取决于并发症和动脉瘤类型。大多数情况下,治疗结果被认为是有效的。
术后化疗和药物治疗可降低严重程度的风险。早期诊断 TBAA 至关重要,随后进行手术切除和术后抗结核药物治疗,并进行仔细随访,以防止复发。