Sahu Vineet K, Datta Adrija, Sarkar Tanusree, Gayen Tirthankar, Chatterjee Gobinda
Department of Dermatology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
Department of Dermatology, IPGME&R, Kolkata, West Bengal, India.
Indian J Dermatol. 2022 Mar-Apr;67(2):127-132. doi: 10.4103/ijd.ijd_577_21.
Alopecia areata is an autoimmune disorder affecting the hair-bearing sites of the body. Trichoscopy has recently been practiced in the diagnosis of alopecia areata.
To elicit trichoscopy patterns in alopecia areata and to find out any correlation of trichoscopic findings with disease severity.
Trichoscopy was done on clinically diagnosed cases of alopecia areata and on age and sex-matched controls without hair disorders by using a DL1 dermoscope (magnification: ×10). Observed dermoscopic findings were analyzed to find the correlation with disease severity.
In total, 87 cases and 60 controls were included in the study with the mean age for cases being 25.47 ± 14.07 years. There was male predominance of cases (51; 58.62%). Alopecia in multiple patches was the most common type (42; 48.27%), and scalp was the most common site of involvement (79; 90.8%). Yellow dots (YD), black dots (BD), broken hairs (BH), circle hair (CH), and tapering hairs (TH) or exclamation hair (EH) were found to be statistically significant findings in alopecia areata as compared to controls. Circle hair was significantly associated with total severity of alopecia areata ( = 0.041). Yellow dots had a positive correlation with the number of episodes of alopecia areata (Spearman's rho = 0.273, = 0.0106) and mean severity of alopecia tool (SALT) score ( = 0.0130). No significant association was noted between trichoscopic findings and disease activity, family history, disease associations, or nail involvement.
A constellation of trichoscopic findings helps in establishing the diagnosis of alopecia areata obviating the need for biopsy.
斑秃是一种影响身体毛发部位的自身免疫性疾病。毛发镜检查最近已应用于斑秃的诊断。
明确斑秃的毛发镜检查模式,并找出毛发镜检查结果与疾病严重程度之间的任何相关性。
使用DL1皮肤镜(放大倍数:×10)对临床诊断的斑秃病例以及年龄和性别匹配的无毛发疾病对照者进行毛发镜检查。分析观察到的皮肤镜检查结果,以找出与疾病严重程度的相关性。
该研究共纳入87例病例和60例对照,病例的平均年龄为25.47±14.07岁。病例以男性居多(51例;58.62%)。多发斑片状脱发是最常见的类型(42例;48.27%),头皮是最常受累的部位(79例;90.8%)。与对照组相比,黄点(YD)、黑点(BD)、断发(BH)、圈状发(CH)以及锥形发(TH)或惊叹号发(EH)在斑秃中被发现具有统计学意义。圈状发与斑秃的总体严重程度显著相关(P = 0.041)。黄点与斑秃发作次数呈正相关(Spearman秩相关系数 = 0.273,P = 0.0106)以及与斑秃工具平均严重程度(SALT)评分呈正相关(P = 0.0130)。在毛发镜检查结果与疾病活动度、家族史、疾病关联或指甲受累之间未发现显著关联。
一系列毛发镜检查结果有助于确立斑秃的诊断,无需进行活检。