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影响类风湿关节炎患者睡眠障碍的因素及抑郁在其中的中介作用。

Factors That Influence Sleep Disturbance and the Mediating Effects of Depression on Sleep Disturbance in Patients With Rheumatoid Arthritis.

机构信息

SiWon Lee, BSN, RN , Graduate student, Department of Nursing, Inha University, Incheon, Republic of Korea.

HyunSoo Oh, PhD, RN , Professor, Department of Nursing, Inha University, Incheon, Republic of Korea.

出版信息

Orthop Nurs. 2022;41(5):335-344. doi: 10.1097/NOR.0000000000000880.

DOI:10.1097/NOR.0000000000000880
PMID:36166609
Abstract

Little is known about the nature of relationships between sleep disturbance and influencing factors in rheumatoid arthritis. The purpose of this study was to identify factors that influence sleep disturbance and to evaluate mediating effects of depression on sleep disturbance. A nonexperimental, descriptive, correlational study design was adopted. One hundred patients with rheumatoid arthritis were recruited. Inflammatory status and levels of pain, fatigue, functional disability, depression, and sleep disturbance were measured. The factors that directly influenced sleep disturbance were gender, rheumatoid arthritis duration, serum C-reactive protein level, fatigue, and depression. Depression was found to have mediating effects on the relationships between sleep disturbance and arthritis symptoms. Pain, fatigue, and depression were found to have significant direct or indirect impacts on sleep disturbance. Our findings may improve understanding of sleep disturbance and aid the development of effective nursing management strategies for patients with rheumatoid arthritis suffering from sleep disturbance.

摘要

关于睡眠障碍与类风湿关节炎影响因素之间关系的性质,人们知之甚少。本研究旨在确定影响睡眠障碍的因素,并评估抑郁对睡眠障碍的中介作用。采用非实验性、描述性、相关性研究设计。招募了 100 名类风湿关节炎患者。测量了炎症状态以及疼痛、疲劳、功能障碍、抑郁和睡眠障碍的水平。直接影响睡眠障碍的因素有性别、类风湿关节炎病程、血清 C 反应蛋白水平、疲劳和抑郁。抑郁对睡眠障碍与关节炎症状之间的关系具有中介作用。疼痛、疲劳和抑郁对睡眠障碍有显著的直接或间接影响。我们的研究结果可能有助于提高对睡眠障碍的认识,并为患有睡眠障碍的类风湿关节炎患者制定有效的护理管理策略。