预测欧亚经济联盟反式脂肪政策可避免的心血管疾病死亡人数。

Projecting cardiovascular deaths averted due to trans fat policies in the Eurasian Economic Union.

机构信息

International Institute of Social Studies, Erasmus University Rotterdam, The Hague, The Netherlands.

World Health Organization European Office for the Prevention and Control of Noncommunicable Diseases (NCD Office), Copenhagen, Denmark.

出版信息

Public Health Nutr. 2023 Dec;26(S1):s41-s50. doi: 10.1017/S1368980022001872. Epub 2022 Oct 5.

Abstract

OBJECTIVE

To demonstrate the potential impact on population health if policies designed to reduce population trans fatty acid (TFA) intake are successfully implemented in the Eurasian Economic Union (EAEU) in line with the WHO's guidelines to lower intake of TFA as a percentage of total energy intake to less than 1 %.

DESIGN

A projection exercise was conducted to estimate reductions in CVD-related deaths in countries of the EAEU if TFA policies are implemented in the EAEU. Plausibly causal, annual effects (in %) of Denmark's TFA policy on the evolution of CVD mortality rates were applied to project the potential effects of recently announced TFA policies in Armenia, Belarus, Kazakhstan, Kyrgyzstan and the Russian Federation under three TFA exposure scenarios.

SETTINGS

Member States of the EAEU: Armenia, Belarus, Kazakhstan, Kyrgyzstan and the Russian Federation.

PARTICIPANTS

Data used for the projection exercise were based on estimates from natural experimental evidence from Denmark. National CVD mortality rates used were from WHO and the Organisation for Economic Cooperation and Development datasets.

RESULTS

In all countries and in all scenarios, deaths averted were ≤ 5 deaths/100,000 in year 1 and rose in years 2 and 3. The highest projected impacts in the high-exposure scenario were seen in Kyrgyzstan (39 deaths/100 000), with the lowest occurring in Armenia (24 deaths/100 000).

CONCLUSION

This study demonstrates the potential population health gains that can be derived from effective policies to reduce TFA in line with WHO guidance. Monitoring and surveillance systems are needed to evaluate the effectiveness of the TFA reduction policies in a national context.

摘要

目的

展示如果欧亚经济联盟(EAEU)按照世界卫生组织(WHO)的指导方针成功实施旨在降低人口反式脂肪酸(TFA)摄入量的政策,对人口健康可能产生的影响,即把 TFA 摄入量占总能量摄入的比例降低到 1%以下。

设计

开展了一项预测研究,以估算如果在 EAEU 实施 TFA 政策,EAEU 国家中与 CVD 相关的死亡人数会减少多少。采用丹麦 TFA 政策对 CVD 死亡率演变的潜在因果年度影响(%)来预测亚美尼亚、白俄罗斯、哈萨克斯坦、吉尔吉斯斯坦和俄罗斯联邦最近宣布的 TFA 政策在三种 TFA 暴露情景下的潜在影响。

设置

EAEU 成员国:亚美尼亚、白俄罗斯、哈萨克斯坦、吉尔吉斯斯坦和俄罗斯联邦。

参与者

预测研究中使用的数据基于丹麦自然实验证据的估计。所使用的国家 CVD 死亡率数据来自世界卫生组织和经济合作与发展组织的数据。

结果

在所有国家和所有情景下,第 1 年避免的死亡人数均≤5/10 万,第 2 年和第 3 年上升。在高暴露情景下,预计对吉尔吉斯斯坦的影响最大(39/10 万),而在亚美尼亚的影响最小(24/10 万)。

结论

本研究表明,按照 WHO 指南实施有效降低 TFA 的政策可以带来潜在的人群健康收益。需要监测和监测系统来评估国家背景下 TFA 减少政策的有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f182/10801378/62e69aa7ef73/S1368980022001872_fig1.jpg

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