Fernandez-Flores A, Cassarino D, Colmenero I
Department of Histopathology, University Hospital El Bierzo, Ponferrada, Spain; Department of Cellular Pathology, Hospital de la Reina, Ponferrada, Spain; Research Department, Institute for Biomedical Research of A Coruña (INIBIC), University of A Coruña (UDC), A Coruña, Spain.
Los Angeles Medical Center (LAMC), Southern California Kaiser Permanente, Department of Dermatology, Los Angeles, CA, USA.
Actas Dermosifiliogr. 2023 Mar;114(3):213-228. doi: 10.1016/j.ad.2022.10.035. Epub 2022 Oct 26.
In the field of vascular anomalies, distinguishing between vascular malformations and tumors has become crucial for a correct therapeutic approach. However, the differential diagnosis between these two groups is not always well explained in classical texts, mainly because many vascular malformations are still known with old names that suggest a tumoral nature. Also, genetic and pathogenic knowledge of these entities has greatly increased in recent decades, so researchers and clinicians now have a better understanding of vascular malformations. In this paper, we present the main histopathological tips to recognize and identify a vascular malformation as such. We also contextualize such information in the clinical and pathogenic knowledge for a better understanding of these entities.
在血管异常领域，区分血管畸形和肿瘤对于正确的治疗方法至关重要。然而，经典文献中对这两组疾病的鉴别诊断并不总是解释得很清楚，主要是因为许多血管畸形仍沿用暗示肿瘤性质的旧名称。此外，近几十年来，对这些疾病的遗传学和发病机制的认识有了很大提高，因此研究人员和临床医生现在对血管畸形有了更好的理解。在本文中，我们介绍了识别和鉴定血管畸形的主要组织病理学要点。我们还将这些信息置于临床和发病机制知识的背景中，以便更好地理解这些疾病。
