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一名成年患者的小脑延髓池成熟畸胎瘤。

Mature teratoma of the cisterna magna in an adult patient.

作者信息

Jafri Syeda Kubra Kishwar, Hussain Nasr, Bari Muhammad Ehsan

机构信息

Department of Neurosurgery, Aga Khan University Hospital, Karachi, Pakistan.

出版信息

Surg Neurol Int. 2022 Sep 23;13:432. doi: 10.25259/SNI_628_2022. eCollection 2022.

Abstract

BACKGROUND

Teratomas are a rare subgroup of CNS germ cell tumors and are histologically classified into mature teratomas, immature teratomas, and teratomas with malignant transformation. CNS teratomas are infrequently found in the posterior fossa and pure mature teratomas of posterior fossa are rare especially in adults. We present a case of a young adult female with a mature teratoma in the cisterna magna.

CASE DESCRIPTION

A 26-year-old female presented to the neurosurgery clinic with headache, nausea and vomiting for the past 1 year. She was found to have dysdiadochokinesia on neurological examination. Brain magnetic resonance imaging scan showed a-well defined lesion, hyperintense on T1 and hypointense on T2-weighted sequences located within the cisterna magna. She underwent a suboccipital craniotomy with resection of lesion. Histopathology confirmed the diagnosis of mature cystic teratoma.

CONCLUSION

Mature teratomas located in the posterior fossa among adults are rare in the literature. We report the second case of mature teratoma in the cisterna magna of an adult patient.

摘要

背景

畸胎瘤是中枢神经系统生殖细胞肿瘤中罕见的一个亚组,在组织学上分为成熟畸胎瘤、未成熟畸胎瘤和伴有恶性转化的畸胎瘤。中枢神经系统畸胎瘤很少见于后颅窝,而后颅窝的纯成熟畸胎瘤尤其罕见,在成人中更是如此。我们报告一例年轻成年女性在小脑延髓池发生成熟畸胎瘤的病例。

病例描述

一名26岁女性因过去1年出现头痛、恶心和呕吐到神经外科门诊就诊。神经系统检查发现她有轮替运动障碍。脑部磁共振成像扫描显示在小脑延髓池内有一个边界清晰的病变,在T1加权序列上呈高信号,在T2加权序列上呈低信号。她接受了枕下开颅手术并切除了病变。组织病理学证实为成熟囊性畸胎瘤。

结论

成人后颅窝的成熟畸胎瘤在文献中很少见。我们报告了第二例成年患者小脑延髓池成熟畸胎瘤的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be82/9610102/4f3ebe98fdb5/SNI-13-432-g001.jpg

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