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鞘膜瓣覆盖联合改良Glenn-Anderson法一期修复近端尿道下裂合并阴茎阴囊转位不全的评估

Evaluation of tunica vaginalis flap-covering combined with modified Glenn-Anderson in one-stage repair of proximal hypospadias with incomplete penoscrotal transposition.

作者信息

Wang Xin, Guan Yong, Wu Yong, Wang Cong, Ma Xiong, Zhang Zhenhua, Zhang Dongzheng

机构信息

Department of Pediatric Surgery, Tianjin Children's Hospital, Tianjin, PR China.

出版信息

Front Pediatr. 2022 Dec 13;10:872027. doi: 10.3389/fped.2022.872027. eCollection 2022.

Abstract

OBJECTIVE

To explore a novel repair method for proximal hypospadias with incomplete penoscrotal transposition in children and evaluate its safety and outcomes.

METHODS

A retrospective analysis of clinical data was conducted for 86 children with severe proximal hypospadias with incomplete penoscrotal transposition who were hospitalized in our department between June 2018 and February 2021. In total, 42 patients (Group A) underwent repair following a one-stage method in which tunica vaginalis flap-covering was combined with a modified Glenn-Anderson procedure, while 44 patients (Group B) underwent a two-step repair consisting of tunica vaginalis flap-covering using the Duplay technique and the modified Glenn-Anderson procedure. The two groups were compared on operation time, length of postoperative hospital stay, postoperative complications, and associated costs.

RESULTS

All operations were successful in both groups. No statistical difference was observed between the two groups in incidence of stenosis of the urinary meatus (2.38% vs. 4.54%,  = 0.279), urethral stricture (2.38% vs. 2.27%,  = 0.948), urinary fistula (7.14% vs. 6.82%,  = 0.907), or urinary infection (7.14% vs. 4.55%,  = 0.309). Additionally, there was no statistical difference between the groups in operation time (63.21 ± 5.20 vs. 62.07 ± 4.47 min,  = 0.059), postoperative off-bed time (7.02 ± 1.32 vs. 6.84 ± 1.20 days,  = 0.456), or duration of hospitalization (10.55 ± 1.15 vs. 10.15 ± 1.45 days,  = 0.092). However, Group B patients underwent an additional second-stage operation, incurring extra costs. Three months after surgery, Group A were judged more positively on the PPPS (specifically receiving higher scores on shaft skin and general appearance) by both the parents (shaft skin: 2.10 ± 0.82 vs. 1.93 ± 0.62,  = 0.024; general appearance: 2.16 ± 0.91 vs. 1.93 ± 0.72,  = 0.042) and the surgeon (shaft skin: 2.42 ± 0.70 vs. 2.25 ± 0.58,  = 0.025; general appearance: 2.38 ± 0.69 vs. 2.29 ± 0.51,  = 0.041). In most cases, the parents and surgeon were satisfied with the appearance of the genitals after one-stage repair.

CONCLUSION

The advantages of the novel repair technique include use of a single-stage operation, producing a better appearance at a lower cost. The tunica vaginalis flap-covering method is not only demonstrated to be safe and effective, but it is also a simpler method than the conventional operation.

摘要

目的

探索一种针对小儿近端尿道下裂合并阴茎阴囊转位不全的新型修复方法,并评估其安全性和效果。

方法

对2018年6月至2021年2月在我科住院的86例重度近端尿道下裂合并阴茎阴囊转位不全患儿的临床资料进行回顾性分析。其中,42例患者(A组)采用一期手术修复,即采用鞘膜瓣覆盖联合改良Glenn-Anderson手术;44例患者(B组)采用两步修复法,包括使用Duplay技术进行鞘膜瓣覆盖和改良Glenn-Anderson手术。比较两组的手术时间、术后住院时间、术后并发症及相关费用。

结果

两组手术均成功。两组在尿道口狭窄发生率(2.38%对4.54%,P = 0.279)、尿道狭窄发生率(2.38%对2.27%,P = 0.948)、尿瘘发生率(7.14%对6.82%,P = 0.907)或泌尿系统感染发生率(7.14%对4.55%,P = 0.309)方面均无统计学差异。此外,两组在手术时间(63.21±5.20对62.07±4.47分钟,P = 0.059)、术后离床时间(7.02±1.32对6.84±1.20天,P = 0.456)或住院时间(10.55±1.15对10.15±1.45天,P = 0.092)方面也无统计学差异。然而,B组患者需额外进行二期手术,产生了额外费用。术后3个月,A组在阴茎外观评分量表(PPPS)上(特别是在阴茎体皮肤和整体外观方面得分更高),得到了家长(阴茎体皮肤:2.10±0.82对1.93±0.62,P = 0.024;整体外观:2.16±0.91对1.93±0.72,P = 0.042)和外科医生(阴茎体皮肤:2.42±0.70对2.25±0.58,P = 0.025;整体外观:2.38±0.69对2.29±0.51,P = 0.041)更积极的评价。在大多数情况下,家长和外科医生对一期修复后的生殖器外观感到满意。

结论

这种新型修复技术的优点包括采用单阶段手术,以较低成本获得更好的外观。鞘膜瓣覆盖法不仅被证明是安全有效的,而且比传统手术更简单。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e35/9792690/d390b7127806/fped-10-872027-g001.jpg

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