Jin Wen-Yuan, Wu Ling-Ling, Hu Li-Fei, Li Wen-Hao, Song Chao, Wang Yan-Yan, Liu Xiao-Lin, Zhu Zhi-Wei
Department of Developmental Behavioral Pediatrics, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.
Front Pediatr. 2023 Jan 9;10:972643. doi: 10.3389/fped.2022.972643. eCollection 2022.
The present study was aimed at investigating the intelligence profiles and adaptive behaviors of children with high-functioning autism spectrum disorder (HFASD) and developmental speech and language disorders (DSLDs). We compared the similarities and differences of cognitive capabilities and adaptive functions and explored their correlations in the HFASD and DSLDs groups.
128 patients with HFASD, 111 patients with DSLDs and 114 typically developing (TD) children were enrolled into our study. Wechsler Intelligence Scale for Children-IV (WISC-IV) and Adaptive Behavior Assessment System-II (ABAS-II) were respectively applied to evaluate intelligence profiles and adaptive behaviors. Intelligence quotient (IQ) scores and adaptive functioning scores among the HFASD, DSLDs and TD groups were compared through one-way ANOVA. Pearson correlation coefficient was applied to examine the relationships between WISC indices and ABAS domains.
Outcomes showed significantly poorer intelligence profiles and adaptive behaviors in HFASD and DSLDs groups. Both children with HFASD and DSLDs demonstrated impairments in verbal comprehension and executive functions. Processing speed and working memory were the predominant defects of children with HFASD and DSLDs in the field of executive functions, respectively. Whereas perceptual reasoning was a relative strength for them. Children with DSLDs had balanced scores of all the domains in ABAS-II; nevertheless, HFASD individuals demonstrated striking impairments in Social domain. Correlation analysis showed IQs of children with HFASD were positively correlated with all the domains and General Adaptive Composite (GAC) of ABAS-II. Additionally, IQs were positively correlated with Conceptual domain and GAC for children with DSLDs. Compared with DSLDs group, intelligence displayed stronger correlations with adaptive behaviors in HFASD group.
Our study expanded insights regarding intelligence profiles and adaptive behaviors of children with HFASD and DSLDs. Moreover, this study made breakthroughs in discovering positive correlations between IQs and adaptive functions in the two neurodevelopmental disorders.
本研究旨在调查高功能自闭症谱系障碍（HFASD）儿童及发育性言语和语言障碍（DSLD）儿童的智力特征和适应性行为。我们比较了HFASD组和DSLD组认知能力和适应性功能的异同，并探讨了它们之间的相关性。
128例HFASD患者、111例DSLD患者和114例发育正常（TD）儿童纳入本研究。分别采用韦氏儿童智力量表第四版（WISC-IV）和适应性行为评估系统第二版（ABAS-II）评估智力特征和适应性行为。通过单因素方差分析比较HFASD组、DSLD组和TD组的智商（IQ）得分和适应性功能得分。采用Pearson相关系数检验WISC指标与ABAS领域之间的关系。
结果显示，HFASD组和DSLD组的智力特征和适应性行为明显较差。HFASD儿童和DSLD儿童在言语理解和执行功能方面均有损害。处理速度和工作记忆分别是HFASD儿童和DSLD儿童在执行功能领域的主要缺陷。而感知推理是他们的相对优势。DSLD儿童在ABAS-II所有领域的得分均衡；然而HFASD个体在社交领域表现出明显损害。相关分析显示，HFASD儿童的智商与ABAS-II所有领域及一般适应性综合得分（GAC）呈正相关。此外DSLD儿童的智商与概念领域和GAC呈正相关。与DSLD组相比，HFASD组智力与适应性行为的相关性更强。
我们的研究拓展了对HFASD儿童和DSLD儿童智力特征和适应性行为的认识。此外，本研究在发现这两种神经发育障碍中智商与适应性功能之间的正相关方面取得了突破。
Zotero 插件