开角型青光眼合并高度近视患者的超声睫状体成形术
Ultrasound Cyclo Plasty in Patients with Open Angle Glaucoma and High Myopia.
作者信息
Figus Michele, Palma Alessandro, Covello Giuseppe, Agnifili Luca, Posarelli Chiara
机构信息
Ophthalmology, Department of Surgical, Medical, Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa.
Ophthalmology, Department of Medicine and Aging Science, University G. D'Annunzio, Chieti-Pescara, Italy.
出版信息
J Glaucoma. 2023 May 1;32(5):420-425. doi: 10.1097/IJG.0000000000002185. Epub 2023 Feb 10.
PRCIS
Ultrasound cyclo plasty (UCP) using high-intensity focused ultrasound is an effective and safe procedure in lowering intraocular pressure (IOP) in patients with glaucoma, even in those with high myopia.
PURPOSE
This study aimed to evaluate the efficacy and safety of UCP in glaucoma patients with high myopia.
MATERIALS AND METHODS
In this retrospective, single-center study, we enrolled 36 eyes divided into 2 groups based on axial length: group A (≥26.00 mm) and group B (<26.00 mm). We collected data about visual acuity, Goldmann applanation tonometry, biomicroscopy, and visual field before the procedure and at 1, 7, 30, 60, 90, 180, and 365 days after the procedure.
RESULTS
Mean IOP significantly decreased in both groups after treatment ( P <0.001). Mean IOP reduction from baseline to the last visit was 9.8±6.6 mmHg (38.7%) in group A and 9.6±6.3 mmHg (34.8%) in group B ( P <0.001). Mean IOP at the last visit was 15.8±4.1 mmHg in the myopic group and 18.1±5.6 mmHg in the non-myopic one. Regarding the number of IOP-lowering eyedrops being taken by our patients, statistically significant differences were found between groups A and B neither at baseline (2.8±0.9 and 2.6±1.0; P =0.568) nor 1 year after the procedure (2.5±1.1 and 2.6±1.1; P =0.762). No major complications occurred. All minor adverse events resolved within a few days.
CONCLUSION
UCP seems to be an effective and well-tolerated strategy to lower IOP in glaucoma patients with high myopia.
PRCIS
使用高强度聚焦超声的超声睫状体成形术(UCP)是降低青光眼患者眼压(IOP)的一种有效且安全的方法,即使是高度近视患者。
目的
本研究旨在评估UCP对高度近视青光眼患者的疗效和安全性。
材料与方法
在这项回顾性单中心研究中,我们根据眼轴长度将36只眼分为两组:A组(≥26.00毫米)和B组(<26.00毫米)。我们收集了手术前以及手术后1天、7天、30天、60天、90天、180天和365天的视力、Goldmann压平眼压测量、生物显微镜检查和视野数据。
结果
两组治疗后平均眼压均显著降低(P<0.001)。从基线到最后一次随访,A组平均眼压降低9.8±6.6毫米汞柱(38.7%),B组降低9.6±6.3毫米汞柱(34.8%)(P<0.001)。近视组最后一次随访时的平均眼压为15.8±4.1毫米汞柱,非近视组为18.1±5.6毫米汞柱。关于患者使用的降眼压眼药水数量,A组和B组在基线时(2.8±0.9和2.6±1.0;P=0.568)以及手术后1年(2.5±1.1和2.6±1.1;P=0.762)均未发现统计学显著差异。未发生重大并发症。所有轻微不良事件在几天内均得到缓解。
结论
UCP似乎是降低高度近视青光眼患者眼压的一种有效且耐受性良好的策略。