Suppr超能文献

采用小崎技术的主动脉瓣重建手术:单中心初步结果

[Aortic valve reconstruction surgery with Ozaki technique: initials results from a single center].

作者信息

Ríos-Ortega Josías C, Aranda-Pretell Necemio, Talledo-Paredes Luisa, Dávila-Durand Manuel, Reyes-Torres Andrés, Pérez-Valverde Yemmy, Morón-Castro Julio

机构信息

Cardiovascular Surgery Department, National Cardiovascular Institute, EsSalud, Lima, Peru.

Master's Program in Health Teaching and Research, Nacional University of San Marcos, Lima, Peru.

出版信息

Arch Cardiol Mex. 2023 Jul 27;93(3):308-317. doi: 10.24875/ACM.22000169.

Abstract

BACKGROUND

Aortic valve (AV) replacement is the gold standard treatment for severe symptomatic AV disease. Recently, AV reconstruction surgery (Ozaki procedure) emerges as a surgical alternative with good results in the medium term.

METHODS

We retrospectively analyzed 37 patients who underwent AV reconstruction surgery between January 2018 and June 2020 in a national reference center in Lima, Peru. The median age was 62 years, interquartile range (IQR: 42-68). The main indication for surgery was AV stenosis (62.2%), in most cases due to bicuspid valve (19 patients, 51.4%). Twenty-two (59.4%) patients had another pathology with surgical indication associated to AV disease, 8 (21.6%) had dilatation of the ascending aorta with indication for replacement.

RESULTS

One in-hospital death occurred (1/38, 2.7%) due to perioperative myocardial infarction. There was a significant reduction in the medians of the peak (70 mmHg, CI 95% = 50.03-79.86 vs. 14 mmHg, CI 95% = 11.93-17.5, p < 0.0001) and mean (45.5 mmHg CI 95% = 30.6-49.68 vs. 7 mmHg, CI 95% = 5.93-9.6, p < 0.0001) AV gradients when we compared baseline characteristics with first 30-days results. In an average of 19 (± 8.9) months of follow-up, survival, reoperation-free survival for valve dysfunction, and survival free of AV insufficiency ≥ II were 97.3%, 100% and 91.9%, respectively. Significant reduction in the medians of the peak and mean AV gradients was maintained.

CONCLUSIONS

AV reconstruction surgery showed optimal results in term of mortality, reoperation-free survival, and hemodynamic characteristics of the neo-AV.

摘要

背景

主动脉瓣置换术是重度症状性主动脉瓣疾病的金标准治疗方法。最近,主动脉瓣重建手术(尾崎手术)作为一种手术替代方案出现,中期效果良好。

方法

我们回顾性分析了2018年1月至2020年6月在秘鲁利马的一个国家参考中心接受主动脉瓣重建手术的37例患者。中位年龄为62岁,四分位间距(IQR:42 - 68)。手术的主要指征是主动脉瓣狭窄(62.2%),大多数情况下是由于二叶式瓣膜(19例患者,51.4%)。22例(59.4%)患者有与主动脉瓣疾病相关的其他手术指征的病理情况,8例(21.6%)有升主动脉扩张并有置换指征。

结果

1例患者因围手术期心肌梗死在院内死亡(1/38,2.7%)。当我们将基线特征与前30天结果进行比较时,主动脉瓣峰值(70 mmHg,95%CI = 50.03 - 79.86 vs. 14 mmHg,95%CI = 11.93 - 17.5,p < 0.0001)和平均(45.5 mmHg,95%CI = 30.6 - 49.68 vs. 7 mmHg,95%CI = 5.93 - 9.6,p < 0.0001)梯度的中位数有显著降低。在平均19(± 8.9)个月的随访中,生存率、无瓣膜功能障碍再次手术生存率以及无≥II级主动脉瓣关闭不全生存率分别为97.3%、100%和91.9%。峰值和平均主动脉瓣梯度的中位数保持显著降低。

结论

主动脉瓣重建手术在死亡率、无再次手术生存率和新主动脉瓣的血流动力学特征方面显示出最佳效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40b0/10406489/b6b53bdcdb46/7567AX223-ACM-93-308-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验