Sweazey R D, Bradley R M
J Comp Neurol. 1986 Mar 22;245(4):471-82. doi: 10.1002/cne.902450404.
Afferent and efferent central connections of the lingual-tonsillar branch of the glossopharyngeal nerve (LT-IX) and the superior laryngeal nerve (SLN) in the lamb were traced with horseradish peroxidase (HRP) histochemistry. After entering the brainstem, most LT-IX and SLN afferent fibers turned caudally in the solitary tract (ST). Some afferent fibers of LT-IX terminated in the medial nucleus of the solitary tract slightly caudal to their level of entry. The remaining fibers projected to the dorsolateral, ventrolateral, and interstitial areas of the nucleus of the solitary tract (NST) at the level of the area postrema. Superior laryngeal nerve afferent fibers terminated extensively in the medial and ventral NST at levels near the rostral pole of the area postrema. Further caudal, near the level of obex, SLN afferent terminations were concentrated in the region ventrolateral to the ST and in the interstitial NST. The caudal extent of LT-IX and the rostral extent of SLN terminals projected to similar levels of the NST, but only a relatively small proportion of the total projections overlapped. Lingual-tonsillar and SLN fibers also coursed rostrally to terminate in the caudal pons within and medial to the dorsomedial principal sensory trigeminal nucleus. Other labeled afferent fibers traveled caudally in the dorsal spinal trigeminal tract to terminate in the dorsal two-thirds of the spinal trigeminal nucleus at the level of obex. Large numbers of labeled cells with fibers in the LT-IX or SLN were located in the ipsilateral rostral nucleus ambiguus and surrounding reticular formation. Fewer labeled cells were observed in the inferior salivatory nucleus following HRP application to either the LT-IX or SLN. The LT-IX and SLN projections to areas of the NST associated with upper airway functions, like swallowing and respiration, suggest an important role for these two nerves in the initiation and control of airway reflexes.
运用辣根过氧化物酶（HRP）组织化学技术，追踪了羔羊舌咽神经舌扁桃体支（LT-IX）和喉上神经（SLN）的传入和传出中枢连接。进入脑干后，大多数LT-IX和SLN传入纤维在孤束（ST）内转向尾侧。LT-IX的一些传入纤维在其进入水平稍尾侧的孤束内侧核终止。其余纤维投射到最后区水平的孤束核（NST）的背外侧、腹外侧和间隙区。喉上神经传入纤维在最后区嘴侧极附近的水平广泛终止于NST的内侧和腹侧。再向尾侧，在闩平面附近，SLN传入终末集中在ST腹外侧区域和间隙性NST。LT-IX的尾侧范围和SLN终末的嘴侧范围投射到NST的相似水平，但总投射中只有相对较小比例重叠。舌扁桃体和SLN纤维也向嘴侧走行，终止于脑桥尾侧的背内侧主要感觉三叉神经核内及其内侧。其他标记的传入纤维在背侧脊髓三叉神经束中向尾侧走行，在闩平面终止于脊髓三叉神经核的背侧三分之二。LT-IX或SLN中有大量纤维的标记细胞位于同侧嘴侧疑核和周围网状结构。将HRP应用于LT-IX或SLN后，在下涎核中观察到的标记细胞较少。LT-IX和SLN投射到与上呼吸道功能（如吞咽和呼吸）相关的NST区域，表明这两条神经在气道反射的启动和控制中起重要作用。
