系统性自身免疫性风湿病中的周围神经病变——诊断与治疗

Peripheral Neuropathy in Systemic Autoimmune Rheumatic Diseases-Diagnosis and Treatment.

作者信息

De Souza Jean Marcos, Trevisan Thiago Junqueira, Sepresse Samara Rosa, Londe Ana Carolina, França Júnior Marcondes Cavalcante, Appenzeller Simone

机构信息

Department of Internal Medicine, School of Medical Science, University of Campinas, Campinas 13083881, Brazil.

Department of Orthopedics, Rheumatology and Traumatology, School of Medical Science, University of Campinas, Campinas 13084971, Brazil.

出版信息

Pharmaceuticals (Basel). 2023 Apr 14;16(4):587. doi: 10.3390/ph16040587.

DOI:10.3390/ph16040587

PMID:37111344

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10141986/

Abstract

Peripheral neuropathy (PN) is frequently observed in systemic rheumatic diseases and is a challenge in clinical practice. We aimed to review the evidence on the subject and proposed a comprehensive approach to these patients, facilitating diagnosis and management. We searched the MEDLINE database for the terms (and its respective Medical Subject Headings (MeSH) terms): "peripheral neuropathy" AND "rheumatic diseases" OR "systemic lupus erythematosus", "rheumatoid arthritis", "Sjogren syndrome", and "vasculitis" from 2000 to 2023. This literature review focuses on the diagnostic workup of PNs related to systemic lupus erythematosus, Sjögren's syndrome, rheumatoid arthritis, and systemic vasculitis. For every type of PN, we provide a pragmatic flowchart for diagnosis and also describe evidence-based strategies of treatment.

摘要

周围神经病变（PN）在系统性风湿性疾病中经常出现，是临床实践中的一项挑战。我们旨在回顾该主题的证据，并为这些患者提出一种全面的方法，以促进诊断和管理。我们在MEDLINE数据库中搜索了2000年至2023年的术语（及其相应的医学主题词（MeSH）术语）：“周围神经病变”以及“风湿性疾病”或“系统性红斑狼疮”、“类风湿性关节炎”、“干燥综合征”和“血管炎”。本综述聚焦于与系统性红斑狼疮、干燥综合征、类风湿性关节炎和系统性血管炎相关的周围神经病变的诊断检查。对于每种类型的周围神经病变，我们提供了一个实用的诊断流程图，并描述了基于证据的治疗策略。