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睡眠参数与慢性肾脏病的关系:伊朗拉万萨尔队列研究的结果。

Association between sleep parameters and chronic kidney disease: findings from iranian ravansar cohort study.

机构信息

Sleep Disorders Research Center, Kermanshah University of Medical sciences, Kermanshah, Iran.

Department of Inorganic Chemistry, Faculty of Chemistry, Razi University, Kermanshah, Iran.

出版信息

BMC Nephrol. 2023 May 17;24(1):136. doi: 10.1186/s12882-023-03177-3.

Abstract

INTRODUCTION

The relationship between sleep duration and chronic kidney disease (CKD) has received relatively little attention in the Kurdish community. Considering the ethnic diversity of Iran and the importance of the Kurdish community, the present study investigated the association between sleep parameters and CKD among a large sample of Iranian-Kurds.

METHODS

This cross-sectional study was conducted among 9,766 participants (M: 47.33, SD = 8.27, 51% female) from the Ravansar Non Communicable Disease (RaNCD) cohort study database. Logistic regression analyses were applied to examine the association between sleep parameters and CKD.

RESULTS

Results showed that prevalence of CKD was detected in 1,058 (10.83%) individuals. Time to fall asleep (p = 0.012) and dozing off during the day (p = 0.041) were significantly higher in the non-CKD group compared to the CKD group. Daytime napping and dozing off during the day in females with CKD were significantly more than males with CKD. A long sleep duration (> 8 h/day) was associated with 28% (95% CI: 1.05, 1.57) higher odds of CKD compared to normal sleep duration (7 h/d), after adjusting for confounding factors. Participants who experienced leg restlessness had a 32% higher probability of developing CKD than those who did not experience leg restlessness (95% CI: 1.03, 1.69).

CONCLUSION

Results suggest that sleep duration and leg restlessness may be associated with an increased likelihood of CKD. Consequently, regulating sleep parameters may play a role in improving sleep and preventing CKD.

摘要

简介

睡眠时长与慢性肾脏病(CKD)之间的关系在库尔德社区中受到的关注相对较少。考虑到伊朗的民族多样性以及库尔德社区的重要性,本研究调查了在一个大型伊朗库尔德人群样本中,睡眠参数与 CKD 之间的关联。

方法

本横断面研究在 Ravansar 非传染性疾病(RaNCD)队列研究数据库中的 9766 名参与者(男性:47.33,SD=8.27,51%为女性)中进行。应用逻辑回归分析来检验睡眠参数与 CKD 之间的关系。

结果

结果显示,1058 名(10.83%)个体患有 CKD。与非 CKD 组相比,CKD 组入睡时间(p=0.012)和白天打盹(p=0.041)显著增加。女性 CKD 患者白天小睡和白天打盹的次数明显多于男性 CKD 患者。与正常睡眠时间(7 小时/天)相比,睡眠时间较长(>8 小时/天)与 CKD 风险增加 28%(95%CI:1.05,1.57)相关,校正混杂因素后。与没有腿部不安的患者相比,腿部不安的患者发生 CKD 的可能性高 32%(95%CI:1.03,1.69)。

结论

结果表明,睡眠时长和腿部不安可能与 CKD 的发生几率增加有关。因此,调节睡眠参数可能在改善睡眠和预防 CKD 方面发挥作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4a0/10193690/b6df7543bdd3/12882_2023_3177_Fig1_HTML.jpg

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