Department of Public Health, Institute of Health Sciences, Dambi Dollo University, Dambi Dollo, Ethiopia.
Department of Epidemiology, College of Public Health, Jimma University, Jimma, Ethiopia.
Vasc Health Risk Manag. 2023 Aug 25;19:527-541. doi: 10.2147/VHRM.S399815. eCollection 2023.
Stroke is the leading cause of cardiovascular disease death in sub-Saharan Africa and the second leading cause of mortality worldwide. In 2016, 6.23% of all fatalities in Ethiopia were stroke-related.
To assess survival status and predictors of mortality among adult stroke patients admitted to Jimma University Medical Center from April 1/2017 to March 31/2022.
A retrospective cohort study was conducted on 480 adult stroke patients selected by simple random sampling from patients admitted to the Jimma University Medical Center Stroke Unit from April 1, 2017 to March 31, 2022. Data were extracted from May to June 2022 and entered Epi-data v.3.1 and analyzed by R v.4.2. The Kaplan-Meier curve with Log rank test was used to estimate survival time and to compare survival experience between categories of explanatory variables. The Cox regression model was computed to identify predictors of survival status in stroke patients. Then the 95% CI of the hazard ratio was set with corresponding p-value < 0.05 to declare statistical significance.
During 4350 person-days of follow-up; 88 (18.33%) patients died; resulting in an incidence mortality of 20.23 per 1000 person-days, with a median survival time of 38 days. Glasgow coma score <8 on admission (AHR = 7.71; 95% CI: 3.78, 15.69), dyslipidemia (AHR = 3.96; 95% CI: 2.04, 7.69), aspiration pneumonia (AHR 2.30; 95% CI: 1.23-4.26), and increased intracranial pressure (AHR = 4.27; 95% CI: 2.33, 7.81), were the independent predictors of the time until death.
The incidence of stroke mortality was higher at the seven and fourteen days. Glasgow Coma Scale, increased intracranial pressure, dyslipidemia, and aspiration pneumonia were independent predictors of mortality.
在撒哈拉以南非洲，中风是心血管疾病死亡的主要原因，也是全球死亡的第二大原因。2016 年，埃塞俄比亚所有死亡人数中，有 6.23%与中风有关。
评估 2017 年 4 月 1 日至 2022 年 3 月 31 日期间在吉姆马大学医学中心接受治疗的成年中风患者的生存状况和死亡预测因素。
这是一项回顾性队列研究，通过简单随机抽样从 2017 年 4 月 1 日至 2022 年 3 月 31 日期间在吉姆马大学医学中心中风病房接受治疗的患者中选择了 480 名成年中风患者。数据于 2022 年 5 月至 6 月提取，并输入 Epi-data v.3.1 进行分析。采用 Kaplan-Meier 曲线和 Log rank 检验来估计生存时间，并比较解释变量类别之间的生存经验。采用 Cox 回归模型来确定中风患者生存状况的预测因素。然后设置危险比的 95%置信区间，并将相应的 p 值<0.05 定义为统计学意义。
在 4350 人天的随访期间，有 88 名（18.33%）患者死亡，发病率死亡率为每 1000 人天 20.23 人，中位生存时间为 38 天。入院时格拉斯哥昏迷评分<8（AHR = 7.71；95%CI：3.78，15.69）、血脂异常（AHR = 3.96；95%CI：2.04，7.69）、吸入性肺炎（AHR = 2.30；95%CI：1.23，4.26）和颅内压升高（AHR = 4.27；95%CI：2.33，7.81）是死亡时间的独立预测因素。
中风死亡率在第 7 天和第 14 天较高。格拉斯哥昏迷评分、颅内压升高、血脂异常和吸入性肺炎是死亡的独立预测因素。
