M Sivaranjani, Gopal Selvarajan, P M Raghuraman, C R K Balaji, N Ranjana
Assistant Professor, Department of ENT, SRM medical college hospital and research centre, Kanchipuram, Tamil Nadu India.
Professor and Head, Department of ENT, SRM Medical College hospital and research centre, Kanchipuram, Tamil Nadu, India.
Indian J Otolaryngol Head Neck Surg. 2023 Dec;75(4):3449-3452. doi: 10.1007/s12070-023-03945-5. Epub 2023 Jun 27.
: Rhinitis is defined as inflammation of nasal mucosa. Allergic rhinitis is the most common type of chronic rhinitis with increasing prevalence. Tests such as nasal smear for eosinophilia, Skin prick test, Serum absolute eosinophil count and Immunoglobulin IgE helps us in diagnosis of allergic rhinitis. : To evaluate the efficacy of the nasal smear for eosinophilia and blood absolute eosinophil count tests to diagnose allergic rhinitis in patients with varied severity of symptoms. : In this prospective study, all patients above 12 years of age with symptoms suggestive of allergic rhinitis were enrolled in our study. Severity assessment was done by visual analog scoring and Total nasal outcome scoring. Diagnostic nasal endoscopy with nasal smear for eosinophilia, complete blood count and blood absolute eosinophil count tests were done. : A total of 60 patients were enrolled in the present study. Age ranged from 13 to 55 years with female preponderance. The most common symptom was rhinorrhea found in 100% of study population, followed by sneezing present in 57 (93.5%) patients. 10 out of 12 patients with mild intermittent symptoms had < 5% of eosinophil elicited in nasal smear and 2 patients had negative smear of eosinophils. Only 13% had mild eosinophilia. In this study, in those patients with mild intermittent symptoms neither nasal smear eosinophilia nor Blood absolute eosinophil count was found to be significant. : Nasal smear cytology and blood absolute eosinophil count were found to be significant only in patients with moderate-severe symptoms. Those patients with mild intermittent symptoms need not be tested as it will be insignificant. In these patients, we must rely on the visual analogue score based on the severity of symptoms rather than laboratory tests.
The online version contains supplementary material available at 10.1007/s12070-023-03945-5.
鼻炎被定义为鼻黏膜的炎症。变应性鼻炎是慢性鼻炎最常见的类型，其患病率呈上升趋势。诸如鼻涂片嗜酸性粒细胞检查、皮肤点刺试验、血清嗜酸性粒细胞绝对计数和免疫球蛋白IgE等检查有助于我们诊断变应性鼻炎。：评估鼻涂片嗜酸性粒细胞检查和血液嗜酸性粒细胞绝对计数检查在诊断症状严重程度各异的变应性鼻炎患者中的疗效。：在这项前瞻性研究中，所有12岁以上有疑似变应性鼻炎症状的患者均纳入我们的研究。通过视觉模拟评分和总鼻结局评分进行严重程度评估。进行了诊断性鼻内镜检查及鼻涂片嗜酸性粒细胞检查、全血细胞计数和血液嗜酸性粒细胞绝对计数检查。：本研究共纳入60例患者。年龄在13至55岁之间，女性居多。最常见的症状是流涕，在100%的研究人群中出现，其次是打喷嚏，57例（93.5%）患者出现。12例轻度间歇性症状患者中，10例鼻涂片嗜酸性粒细胞比例<5%，2例嗜酸性粒细胞涂片阴性。只有13%有轻度嗜酸性粒细胞增多。在本研究中，对于那些有轻度间歇性症状的患者，未发现鼻涂片嗜酸性粒细胞增多和血液嗜酸性粒细胞绝对计数有显著意义。：鼻涂片细胞学检查和血液嗜酸性粒细胞绝对计数仅在中重度症状患者中具有显著意义。那些有轻度间歇性症状的患者无需进行检查，因为检查结果无意义。在这些患者中，我们必须依靠基于症状严重程度的视觉模拟评分，而不是实验室检查。
在线版本包含可在10.1007/s12070 - 023 - 03945 - 5获取的补充材料。
