Alharajin Rasmah S, Al Moaibed Hessa S, Al Khalifah Fatimah K
Department of University Health Clinic, King Saud Bin Abdulaziz University for Health Sciences, Al Ahsa, SAU.
Department of Family Medicine, King Abdulaziz Hospital, Ministry of the National Guard, Al Ahsa, SAU.
Cureus. 2023 Nov 23;15(11):e49317. doi: 10.7759/cureus.49317. eCollection 2023 Nov.
Background and aim Diabetic neuropathy is one of the most common long-term complications of diabetes. A frequent presentation of neuropathy is painful diabetic peripheral neuropathy (PDPN), which is associated with morbidity and disability among patients with diabetes. This study aims to estimate the prevalence of PDPN and its associated factors among patients with type 2 diabetes mellitus (T2DM) attending primary healthcare (PHC) in Al Ahsa. Methodology A cross-sectional study was conducted on patients with diabetes at National Guard PHC clinics in Al Ahsa, Saudi Arabia. An interview-administered questionnaire was used to collect information about clinicodemographic characteristics, and the Douleur Neuropathique-4 (DN4) questionnaire was used to identify the presence of PDPN. Results A total of 342 patients with T2DM were included. The prevalence of PDPN was 29.8%. Patients' ages ranged from 25-70 years, with a mean age of 48.5 ± 12.3 years. The majority were female (118, 52.6%), with obesity detected among 115 (33.6%) individuals. Significant predictors of PDPN included noncompliance to treatment (odds ratio [OR] = 5.9, = 0.001), female gender (OR = 3.5, = 0.001), presence of other comorbidities (OR = 1.7, = 0.001), and diabetes duration exceeding 15 years (OR = 1.5, = 0.001). Conclusions This study revealed that PDPN was frequent among patients with diabetes in Al Ahsa, which was at an intermediate frequency relative to reported national and global literature levels. Identifying patients who are at high risk and implementing timely interventions are crucial.
背景与目的 糖尿病神经病变是糖尿病最常见的长期并发症之一。神经病变的常见表现是疼痛性糖尿病周围神经病变（PDPN），这与糖尿病患者的发病率和残疾情况相关。本研究旨在估计沙特阿拉伯艾卜哈地区基层医疗保健机构中2型糖尿病（T2DM）患者PDPN的患病率及其相关因素。方法 对沙特阿拉伯艾卜哈地区国民警卫队基层医疗保健诊所的糖尿病患者进行了一项横断面研究。采用访谈式问卷收集临床人口统计学特征信息，并使用神经病理性疼痛-4（DN4）问卷来确定PDPN的存在情况。结果 共纳入342例T2DM患者。PDPN的患病率为29.8%。患者年龄在25至70岁之间，平均年龄为48.5±12.3岁。大多数为女性（118例，52.6%），115例（33.6%）个体存在肥胖。PDPN的显著预测因素包括治疗依从性差（比值比[OR]=5.9，P=0.001）、女性（OR=3.5，P=0.001）、存在其他合并症（OR=1.7，P=0.001）以及糖尿病病程超过15年（OR=1.5，P=0.001）。结论 本研究表明，艾卜哈地区糖尿病患者中PDPN较为常见，相对于已报道的国内和全球文献水平，处于中等频率。识别高危患者并及时实施干预至关重要。
