来自[具体来源1]和[具体来源2]的胞外多糖：生物活性、对肠道微生物群的影响以及发酵乳的流变学。

Exopolysaccharides from and : Bioactivities, gut microbiome effects, and fermented milk rheology.

作者信息

Tarique Mohammed, Ali Abdelmoneim H, Kizhakkayil Jaleel, Liu Shao-Quan, Oz Fatih, Dertli Enes, Kamal-Eldin Afaf, Ayyash Mutamed

机构信息

Department of Food Science, College of Agriculture and Veterinary Medicine, United Arab Emirates University (UAEU), Al Ain, United Arab Emirates.

Department of Food Science, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.

出版信息

Food Chem X. 2023 Dec 15;21:101073. doi: 10.1016/j.fochx.2023.101073. eCollection 2024 Mar 30.

DOI:10.1016/j.fochx.2023.101073

PMID:38235344

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10792183/

Abstract

Exopolysaccharides (EPSs) are carbohydrate polymers that can be produced from probiotic bacteria. This study characterized the EPSs from (EPS-LB13) and (EPS-MLB10) and evaluated their biological and technological potential. The EPSs had high molecular weight and different monosaccharide compositions. The EPSs exhibited various biological activities at 250 mg/L, such as scavenging free radicals (10 % to 88.8 %), enhancing antioxidant capacity (714 to 2848 µg/mL), inhibiting pathogens (53 % to 74 %), and suppressing enzymes and cancer cells (2 % to 83 %), etc. The EPSs supported the growth of beneficial gut bacteria from Proteobacteria, Bacteroidetes, Firmicutes, and Acinetobacter in fecal fermentation with total Short-chain fatty acids production from 5548 to 6023 PPM. Moreover, the EPSs reduced the gelation time of fermented skimmed bovine milk by more than half. These results suggest that the EPSs from LB13 and MLB10 have promising applications in the dairy and pharmaceutical industries.

摘要

胞外多糖（EPSs）是一类可由益生菌产生的碳水化合物聚合物。本研究对[具体菌株1]（EPS-LB13）和[具体菌株2]（EPS-MLB10）产生的胞外多糖进行了表征，并评估了它们的生物学和技术潜力。这些胞外多糖具有高分子量和不同的单糖组成。在250 mg/L浓度下，这些胞外多糖表现出多种生物活性，如清除自由基（10%至88.8%）、增强抗氧化能力（714至2848 μg/mL）、抑制病原体（53%至74%）以及抑制酶和癌细胞（2%至83%）等。在粪便发酵中，这些胞外多糖支持了变形菌门、拟杆菌门、厚壁菌门和不动杆菌属等有益肠道细菌的生长，总短链脂肪酸产量为5548至6023 PPM。此外，这些胞外多糖使发酵脱脂牛乳的凝胶化时间缩短了一半以上。这些结果表明，来自LB13和MLB10的胞外多糖在乳制品和制药行业具有广阔的应用前景。