儿科抗心律失常药物与毒性：临床综述

Pediatric antiarrhythmics and toxicity: A clinical review.

作者信息

Geanacopoulos Alexandra T, Zielonka Benjamin, Fox Miriam T, Kerr Sarah, Chambers Kristina D, Przybylski Robert, Burns Michele M

机构信息

Division of Emergency Medicine Boston Children's Hospital Boston Massachusetts USA.

Department of Pediatrics Harvard Medical School Boston Massachusetts USA.

出版信息

J Am Coll Emerg Physicians Open. 2024 Feb 15;5(1):e13090. doi: 10.1002/emp2.13090. eCollection 2024 Feb.

DOI:10.1002/emp2.13090

PMID:38371660

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10869663/

Abstract

Antiarrhythmic medications are fundamental in the acute and chronic management of pediatric arrhythmias. Particularly in the pediatric patient population, associated antiarrhythmic toxicities represent important potential adverse effects. Emergency medicine clinicians must be skilled in the detection, workup, and management of antiarrhythmic toxicity. This is a clinical review of the indications, pharmacology, adverse effects, and toxicologic treatment of antiarrhythmics commonly used in the pediatric patient population.

摘要

抗心律失常药物在小儿心律失常的急性和慢性管理中至关重要。特别是在儿科患者群体中，相关的抗心律失常毒性是重要的潜在不良反应。急诊医学临床医生必须熟练掌握抗心律失常毒性的检测、检查和管理。这是一篇关于儿科患者群体常用抗心律失常药物的适应证、药理学、不良反应及毒理学治疗的临床综述。