Roux-en-Y 胃旁路术后早期边缘溃疡:MBSAQIP 数据库分析趋势和预测因素。

Early Marginal Ulcer After Roux-en-Y Gastric Bypass: MBSAQIP Database Analysis of Trends and Predictive Factors.

机构信息

Department of General Surgery, Mayo Clinic, Jacksonville, 4500 San Pablo Rd, Jacksonville, FL, 32224, USA.

出版信息

Obes Surg. 2024 May;34(5):1536-1543. doi: 10.1007/s11695-024-07179-4. Epub 2024 Mar 19.

Abstract

PURPOSE

Marginal ulcer (MU) is a known complication after Roux-en-Y gastric bypass (RYGB) that carries significant morbidity. First, we aimed to determine the trends and the rates of readmission, reintervention, and reoperation of 30-day MU. Second, we aim to determine the predictive factors associated with this complication.

MATERIALS AND METHODS

Patients who had 30-day marginal ulcer (MU) after LRYGB were identified using the 2015-2021 MBSAQIP database. Those who had a 30-day complication other than MU were excluded. Bivariate and logistic regression analyses were performed.

RESULTS

Among 213,104 patients undergoing laparoscopic RYGB, 638 (0.3%) showed 30-day MU. This group of patients required endoscopic interventions, readmissions, and reoperations at rates of 88%, 72%, and 9%, respectively. Predictive factors for 30-day MU after RYGB were renal insufficiency, history of DVT, previous cardiac stent, African American race, chronic steroid use, COPD, therapeutic anticoagulation, anastomotic leak test, GERD, and operative time > 120 min. Additionally, patients who had 30-day MU showed significantly higher rates of overall complications such as pulmonary, cardiac and renal complications, unplanned ICU admission, blood transfusions, venous thromboembolism (VTE), and non-home discharge (p < 0.05). The MU group showed similar rates of 30-day mortality as those without this complication (0.2% vs 0.1%, p = 0.587).

CONCLUSIONS

The incidence of 30-day MU following RYGB was 0.3%. Patients with MU required endoscopic interventions, readmissions, and reoperations at rates of 88%, 72%, and 9%, respectively. Some preoperative and intraoperative factors contributed to an increased risk of 30-day MU.

摘要

目的

边缘性溃疡(MU)是 Roux-en-Y 胃旁路术(RYGB)后的已知并发症,具有显著的发病率。首先,我们旨在确定 30 天 MU 的再入院、再干预和再手术的趋势和比率。其次,我们旨在确定与该并发症相关的预测因素。

材料和方法

使用 2015-2021 年 MBSAQIP 数据库确定接受腹腔镜 RYGB 后 30 天发生 MU 的患者。排除有 30 天 MU 以外的并发症的患者。进行了单变量和逻辑回归分析。

结果

在 213104 例接受腹腔镜 RYGB 的患者中,有 638 例(0.3%)在 30 天内出现 MU。该组患者内镜干预、再入院和再手术的比例分别为 88%、72%和 9%。RYGB 后 30 天发生 MU 的预测因素为肾功能不全、DVT 病史、既往心脏支架、非裔美国人、慢性类固醇使用、COPD、治疗性抗凝、吻合口漏试验、GERD 和手术时间>120 分钟。此外,有 30 天 MU 的患者总体并发症(如肺部、心脏和肾脏并发症、计划外 ICU 入院、输血、静脉血栓栓塞症[VTE]和非家庭出院)的发生率显著更高(p<0.05)。MU 组与无此并发症组的 30 天死亡率相似(0.2%比 0.1%,p=0.587)。

结论

RYGB 后 30 天 MU 的发生率为 0.3%。MU 患者需要内镜干预、再入院和再手术的比例分别为 88%、72%和 9%。一些术前和术中因素增加了 30 天 MU 的风险。

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