Neuman Menahem, Farnsworth Bruce, Sun Xiuli, Sekiguchi Yuki, Wenk Maren, Inoue Hiromi
Department of Gynecoloy, Bar-llan University Israel, Ramat Gan, Israel.
Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing, China.
Ann Transl Med. 2024 Apr 22;12(2):28. doi: 10.21037/atm-23-1769. Epub 2024 Apr 9.
A core concept of the Integral Theory System is that "ligaments are for structure; vagina is for function". The vagina and uterus should be conserved. Because the vagina is an organ, its collagen and elastin, which are so necessary for its function, cannot regenerate once they are removed. Removing the uterus involves severing the descending uterine artery, which is the principal blood supply of the proximal part of the uterosacral ligaments (USLs), and so may cause atrophy, which can cause future incontinence problems because of collagen loss after menopause. The diagnostic algorithm guides which of the five pelvic ligaments need repair. Native ligament plication can be adequate for prolapse/symptom cure, but only in premenopausal women. Postmenopausal women are usually collagen deficient and require collagen-creating tapes or wide-bore polyester sutures to restore structural collagen in the ligaments. Of extreme importance, vaginal tissue excision should be avoided, as consequent scarring may cause "tethered vagina syndrome" (TVS). TVS can cause massive uncontrolled urine loss because the scar tissue in the bladder neck area of the vagina can link the more powerful posterior muscles to the anterior, so the posterior urethra wall is forcibly pulled open, when given the signal to close. Instead of vaginal excision, a "concertina" suture technique re-assigns and shrinks excess vaginal tissue to normal anatomy by 6 weeks. In conclusion, the five key surgical principles of the Integral Theory System are: ligaments are for structure, vagina is for function; structure (prolapse) and function (symptoms) are related; repair the structure and you will restore the function; avoid vaginal excision and hysterectomy; create new collagen to reinforce the damaged ligaments.
整体理论体系的一个核心概念是“韧带负责结构,阴道负责功能”。阴道和子宫应予以保留。因为阴道是一个器官,其功能所必需的胶原蛋白和弹性蛋白一旦被切除就无法再生。切除子宫涉及切断子宫下行动脉,而子宫下行动脉是子宫骶韧带近端的主要血液供应,因此可能导致萎缩,绝经后由于胶原蛋白流失可能会引发未来的失禁问题。诊断算法指导需要修复五条盆腔韧带中的哪一条。对于脱垂/症状的治愈,单纯的韧带折叠术可能就足够了,但仅适用于绝经前女性。绝经后女性通常胶原蛋白缺乏,需要使用能产生胶原蛋白的胶带或宽孔聚酯缝线来恢复韧带中的结构性胶原蛋白。极其重要的是,应避免阴道组织切除,因为随之而来的瘢痕形成可能会导致“束缚性阴道综合征”(TVS)。TVS可导致大量无法控制的尿液流失,因为阴道膀胱颈区域的瘢痕组织可将更强大的后部肌肉与前部相连,所以当接收到关闭信号时,后尿道壁会被强行拉开。“手风琴”缝合技术通过6周时间将多余的阴道组织重新分配并收缩至正常解剖结构,而不是进行阴道切除。总之,整体理论体系的五条关键手术原则是:韧带负责结构,阴道负责功能;结构(脱垂)和功能(症状)相关;修复结构就能恢复功能;避免阴道切除和子宫切除术;制造新的胶原蛋白以加强受损韧带。