寰椎椎弓根螺钉固定术治疗Ⅱ型和颅端Ⅲ型齿突骨折的近期和远期疗效。

Short-term and long-term results of odontoid screw fixation in patients with Type II and rostral Type III dens fractures.

机构信息

Department of Neurosurgery, Sklifosovsky Research Institute for Emergency Medicine, Moscow, Russia.

Department of Neurosurgery, Sklifosovsky Research Institute for Emergency Medicine, Moscow, Russia.

出版信息

Neurocirugia (Astur : Engl Ed). 2024 Sep-Oct;35(5):233-240. doi: 10.1016/j.neucie.2024.05.003. Epub 2024 May 29.

Abstract

OBJECTIVES

To evaluate both the short-term and long-term outcomes of odontoid screw fixation (OSF), identifying potential risk factors for implant-related complications in patients with odontoid fractures.

METHODS

This is a retrospective observational cohort study. Inclusion criteria were as follows: 1) Type II fractures and rostral Type III fractures, according to the Anderson and D'Alonzo classification; 2) patients older than 15 years. Exclusion criteria were: 1) other Type III injuries; 2) osteoporosis confirmed by densitometry or a CT bone density score below 100 Hounsfield units; 3) odontoid fractures related to tumors or aneurysmal bone cysts.

RESULTS

In total, 56 patients were considered for the analysis of short-term results, and 26 patients were evaluated for long-term outcomes. No significant differences were observed in the preoperative imaging data and intraoperative features of OSF between patients with Type II and rostral Type III fractures. The mean operative duration was 63.9 ± 20.9 min, and the mean intraoperative blood loss was 22.1 ± 22.9 ml. Screw cut-out was identified in four patients with rostral Type III fractures (p = 0.04). The rate of screw cut-out was found to correlate with the degree of dens fragment displacement. The bone fusion rate was 95.7%. CT scans identified stable pseudarthrosis in two cases. We observed C2-C3 ankylosis in all cases following partial disc resection. One third of patients with screws placed through the anterior lip of C2 showed no C2-C3 ankylosis. A strong trend towards lateral joint ankylosis formation in patients with a median lateral mass dislocation of 11.9 mm was observed. Most SF-36 scores either matched or exceeded the corresponding normal median values in the published reference database.

CONCLUSIONS

OSF is a reliable treatment method of Type II and rostral Type III odontoid fractures with fragment displacement of 4 mm or less. The minimally invasive OSF through the anterior-inferior lip of C2, using monocortical screw placement and cannulated instruments, without rigid intraoperative head immobilization, is sufficient to achieve favorable clinical and fusion results. This technique reduces the risk of ankylosis in the C2-C3 segment. OSF restore the quality of life for patients with odontoid fractures to levels comparable to those of the general population norm.

摘要

目的

评估齿状突螺钉固定(OSF)的短期和长期结果,确定齿状突骨折患者与植入物相关并发症相关的潜在危险因素。

方法

这是一项回顾性观察队列研究。纳入标准如下:1)根据安德森和达隆佐分类,为 II 型骨折和颅向 III 型骨折;2)年龄大于 15 岁。排除标准为:1)其他 III 型损伤;2)通过骨密度测定或 CT 骨密度评分低于 100 亨氏单位证实的骨质疏松症;3)与肿瘤或动脉瘤样骨囊肿相关的齿状突骨折。

结果

共考虑 56 例患者进行短期结果分析,26 例患者进行长期结果评估。II 型和颅向 III 型骨折患者的术前影像学数据和 OSF 术中特征无显著差异。手术时间平均为 63.9±20.9 分钟,术中出血量平均为 22.1±22.9 毫升。4 例颅向 III 型骨折患者发现螺钉切出(p=0.04)。螺钉切出率与 dens 碎片移位程度相关。骨融合率为 95.7%。CT 扫描在 2 例中发现稳定的假关节。在进行部分椎间盘切除后,所有病例均出现 C2-C3 强直。三分之一的通过 C2 前唇放置螺钉的患者没有 C2-C3 强直。观察到在中侧块脱位 11.9 毫米的患者中,外侧关节强直形成有强烈的趋势。SF-36 评分中的大多数要么与发表的参考数据库中的相应中位数相匹配,要么超过中位数。

结论

OSF 是一种治疗 II 型和颅向 III 型齿状突骨折的可靠方法,骨折块移位小于或等于 4 毫米。通过 C2 前下唇采用微创 OSF,使用单皮质螺钉固定和套管器械,无需刚性术中头部固定,即可获得良好的临床和融合效果。这种技术降低了 C2-C3 节段强直的风险。OSF 将齿状突骨折患者的生活质量恢复到与普通人群正常值相当的水平。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索