Chen Yuan, Chen Yanping, Chen Xiao, Zhai XiaoLi, Zhu Fang, Ye Xiaohua, Ding Jin
Altern Ther Health Med. 2025 Sep;31(5):141-145.
To analyze the potential factors influencing the diagnostic capability of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) and provide medication treatment recommendations for patients with pancreatic solid mass lesions.
A retrospective analysis was conducted on clinical data of 92 patients with pancreatic solid mass lesions who underwent EUS-FNA examination after detection by imaging studies. The diagnostic effectiveness of EUS-FNA was evaluated based on cytological or histological examination results. Logistic regression analysis was subsequently performed to analyze the potential factors influencing the diagnostic capability of EUS-FNA in patients with pancreatic solid mass lesions.
EUS-FNA was successfully performed in all 92 patients, with a puncture success rate of 100.00%. Only one patient experienced transient hyperamylasemia, which resolved with conservative treatment. No other serious complications were observed. Among the 92 patients, 70 patients obtained a definite diagnosis after EUS-FNA (Group A), while 22 patients did not achieve a definite diagnosis (Group B) after the procedure. Univariate analysis showed that lesion size, dilation of the pancreatic duct or bile duct, negative pressure, and suction method were significantly different between Group A and Group B (P < .05). Multivariate logistic regression analysis revealed that lesion size, dilation of the pancreatic duct or bile duct, negative pressure, and suction method were potential factors influencing the diagnostic ability of EUS-FNA in patients with solid pancreatic lesions (P < .05).
EUS-FNA has a high diagnostic value in the evaluation of solid pancreatic lesions. Lesion size, dilation of the pancreatic duct or bile duct, negative pressure, and suction method are potential factors influencing the diagnostic ability of EUS-FNA in patients with solid pancreatic lesions. In terms of medical treatment, specific treatment methods and drug choices should be based on a comprehensive evaluation of the nature of the patient's lesions and the severity of the condition.
分析影响超声内镜引导下细针穿刺抽吸术（EUS-FNA）诊断能力的潜在因素，并为胰腺实性肿块病变患者提供药物治疗建议。
对92例经影像学检查发现胰腺实性肿块病变后接受EUS-FNA检查的患者的临床资料进行回顾性分析。根据细胞学或组织学检查结果评估EUS-FNA的诊断有效性。随后进行Logistic回归分析，以分析影响胰腺实性肿块病变患者EUS-FNA诊断能力的潜在因素。
92例患者均成功进行了EUS-FNA，穿刺成功率为100.00%。仅1例患者出现短暂性高淀粉酶血症，经保守治疗后缓解。未观察到其他严重并发症。92例患者中，70例在EUS-FNA后获得明确诊断（A组），而22例患者在术后未获得明确诊断（B组）。单因素分析显示，A组和B组在病变大小、胰管或胆管扩张、负压和抽吸方法方面存在显著差异（P < .05）。多因素Logistic回归分析显示，病变大小、胰管或胆管扩张、负压和抽吸方法是影响胰腺实性病变患者EUS-FNA诊断能力的潜在因素（P < .05）。
EUS-FNA在评估胰腺实性病变方面具有较高的诊断价值。病变大小、胰管或胆管扩张、负压和抽吸方法是影响胰腺实性病变患者EUS-FNA诊断能力的潜在因素。在药物治疗方面，具体的治疗方法和药物选择应基于对患者病变性质和病情严重程度的综合评估。
