经皮神经电刺激整合在裤子中缓解髋关节手术后患者的术后疼痛:一项随机试验。

Transcutaneous Electrical Nerve Stimulation Integrated into Pants for the Relief of Postoperative Pain in Hip Surgery Patients: A Randomized Trial.

机构信息

Polymeric E-Textile Research Group Swedish School of Textiles University of Borås, Allégatan 1, Borås 501 90, Sweden.

Karolinska University Hospital, Solna, Stockholm 171 76, Sweden.

出版信息

Pain Res Manag. 2024 Jun 27;2024:6866549. doi: 10.1155/2024/6866549. eCollection 2024.

Abstract

BACKGROUND

The effect of transcutaneous electrical nerve stimulation (TENS) on pain and impression of change was assessed during a 2.5-hour intervention on the first postoperative days following hip surgery in a randomized, single-blinded, placebo-controlled trial involving 30 patients.

METHODS

Mixed-frequency TENS (2 Hz/80 Hz) was administered using specially designed pants integrating modular textile electrodes to facilitate stimulation both at rest and during activity. The treatment outcome was assessed by self-reported pain Numerical Rating Scale (NRS) and Patient Global Impression of Change (PGIC) scores at four time points. The ability to perform a 3-meter walk test and the use of analgesics were also evaluated. Group comparison and repeated-measure analysis were carried out using nonparametric statistics.

RESULTS

The active TENS group exhibited significantly higher PGIC scores after 30 minutes, which persisted throughout the intervention (all ≤ 0.001). A reduction in NRS appeared after one hour of active TENS, persisting throughout the intervention (all ≤ 0.05). The median group differences in pain ratings were greater than the minimum clinically important difference, and the analysis of pain trajectories confirmed clinical significance at the individual level. Moreover, patients in the active TENS group were more likely able to perform a 3-meter walk test by the end of the intervention ( = 0.04). Analysis of the opioid-sparing effect of TENS was inconclusive ( = 0.066). No postoperative surgical complications or TENS-related side effects were observed during the study.

CONCLUSION

Mixed-frequency TENS integrated in pants could potentially be an interesting addition to the arsenal of treatments for multimodal analgesia following hip surgery. This trial is registered with NCT05678101.

摘要

背景

在一项涉及 30 名患者的随机、单盲、安慰剂对照试验中,在髋关节手术后的头两天,评估了经皮神经电刺激(TENS)对疼痛和变化印象的影响,干预持续 2.5 小时。

方法

混合频率 TENS(2 Hz/80 Hz)使用专门设计的裤子进行,裤子上集成了模块化的纺织电极,以便在休息和活动时都能进行刺激。通过四个时间点的自我报告疼痛数字评分量表(NRS)和患者整体印象变化(PGIC)评分评估治疗效果。还评估了 3 米步行测试的能力和镇痛药的使用情况。使用非参数统计进行组间比较和重复测量分析。

结果

主动 TENS 组在 30 分钟后 PGIC 评分显著升高,整个干预过程中持续升高(均 ≤ 0.001)。主动 TENS 后 1 小时 NRS 下降,整个干预过程中持续下降(均 ≤ 0.05)。疼痛评分的中位数组间差异大于最小临床重要差异,疼痛轨迹分析在个体水平上证实了临床意义。此外,主动 TENS 组的患者在干预结束时更有可能能够进行 3 米步行测试( = 0.04)。TENS 节省阿片类药物作用的分析结果不确定( = 0.066)。在研究过程中未观察到术后手术并发症或 TENS 相关副作用。

结论

集成在裤子中的混合频率 TENS 可能成为髋关节手术后多模式镇痛治疗武器库中的一个有趣补充。这项试验在 NCT05678101 注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/535b/11323988/385bba852e59/PRM2024-6866549.001.jpg

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