老年人单侧膝骨关节炎的超声影像学参数与股四头肌生物力学特性的差异：一项初步观察性研究。

The Differences in Parameters in Ultrasound Imaging and Biomechanical Properties of the Quadriceps Femoris with Unilateral Knee Osteoarthritis in the Elderly: A Preliminary Observational Study.

机构信息

Department of Orthopedics and Traumatology, The Fifth Clinical College of Guangzhou University of Chinese Medicine, Guangdong Provincial Second Hospital of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Research and Development in Traditional Chinese Medicine, Guangzhou, People's Republic of China.

Department of Osteoarthropathy II, Luoyang Orthopedic-Traumatological Hospital of Henan Province (Henan Provincial Orthopedic Hospital), Luoyang, People's Republic of China.

出版信息

Clin Interv Aging. 2024 Aug 26;19:1479-1491. doi: 10.2147/CIA.S442610. eCollection 2024.

DOI:10.2147/CIA.S442610

PMID:39220855

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11363936/

Abstract

PURPOSE

Our study aims to evaluate differences in muscle parameters of the quadriceps muscles in patients with knee osteoarthritis (KOA) in older adults.

METHODS

The study included 40 patients diagnosed with unilateral knee osteoarthritis in the KOA group (KG) and 40 asymptomatic elderly individuals in the control group (CG). Muscle ultrasonic mean echo intensity and shear modulus, as well as tone and stiffness of the rectus femoris (RF), vastus medialis (VM), and vastus lateralis (VL) were analyzed. Additionally, clinical correlations were performed.

RESULTS

In the KG group, there were significant differences in echo intensity, shear modulus, and tone between the affected and unaffected sides for RF (p=0.003, 0.019, 0.014), while VM showed significant differences in shear modulus and tone (p=0.006, 0.002). Additionally, VL exhibited significant differences in echo intensity, shear modulus, and stiffness (p=0.007, 0.006, 0.010). Compared to the CG group, the KG group showed significant differences in echo intensity of the affected side RF (p=0.001). VM exhibited statistically significant differences in echo intensity and shear modulus (p < 0.001, p=0.008), while VL showed statistically significant differences in echo intensity, tone, and stiffness (p < 0.001, p=0.028, p < 0.001). The correlation results showed that patients with unilateral KOA, VM, and VL echo intensity were correlated with K-L grade (r = 0.443, p=0.004; r = 0.469, p=0.002). The tone of VL was correlated with VAS and WOMAC (r = 0.327, p=0.039; r = 0.344, p=0.030).

CONCLUSION

The parameters of the quadriceps femoris muscle exhibit asymmetry between the affected and unaffected sides in patients with unilateral KOA, as well as a difference between the dominant side of healthy older individuals and the affected side of KOA.

摘要

目的

本研究旨在评估老年膝骨关节炎（KOA）患者股四头肌肌肉参数的差异。

方法

本研究纳入了 40 例单侧膝骨关节炎患者（KOA 组，KG）和 40 例无症状老年人作为对照组（CG）。分析了股直肌（RF）、股内侧肌（VM）和股外侧肌（VL）的超声平均回声强度和剪切模量以及 tone 和 stiffness。同时进行了临床相关性分析。

结果

在 KG 组中，RF 患侧与健侧的回声强度、剪切模量和 tone 有显著差异（p=0.003、0.019、0.014），VM 的剪切模量和 tone 有显著差异（p=0.006、0.002）。此外，VL 的回声强度、剪切模量和 stiffness 也有显著差异（p=0.007、0.006、0.010）。与 CG 组相比，KG 组患侧 RF 的回声强度有显著差异（p=0.001）。VM 的回声强度和剪切模量有显著差异（p<0.001、p=0.008），VL 的回声强度、tone 和 stiffness 也有显著差异（p<0.001、p=0.028、p<0.001）。相关性结果显示，单侧 KOA 患者的 VM 和 VL 回声强度与 K-L 分级呈正相关（r=0.443、p=0.004；r=0.469、p=0.002）。VL 的 tone 与 VAS 和 WOMAC 呈正相关（r=0.327、p=0.039；r=0.344、p=0.030）。