叙利亚冲突期间房颤住院后的六个月紧急再入院情况：一项真实世界观察性队列研究

Six-Month Emergent Readmissions Following Hospitalization for Atrial Fibrillation Amid the Syrian Conflict: A Real-World Observational Cohort Study.

作者信息

Antoun Ibrahim, Alkhayer Alkassem, Alkhayer Alamer, Yazji Khaled, Somani Riyaz, Ng G André, Zakkar Mustafa

机构信息

Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.

Faculty of Medicine, University of Aleppo, Aleppo, Syria.

出版信息

J Cardiovasc Electrophysiol. 2025 Mar;36(3):582-588. doi: 10.1111/jce.16579. Epub 2025 Jan 13.

DOI:10.1111/jce.16579

PMID:39803787

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11903379/

Abstract

BACKGROUND

Atrial fibrillation (AF) is the most common arrhythmia worldwide. However, data regarding readmissions following index admission for AF in the developing world are not well described. This study assessed the rate, predictors, and trends of 6-month readmission after index admission for AF in Syria.

METHODS

We included adult patients who had an index admission with AF to Latakia's tertiary center between July 2021 and November 2023. Patients were monitored for readmission for 6 months after index discharge. Data were taken from the patient's medical notes.

RESULTS

A total of 649 patients were included in the final analysis, of which 320 (49%) were readmitted to the hospital within 6 months following index admission. Cardiac causes were the most common cause of readmission in 76% of patients, of which 70% were AF. Readmitted patients had a higher median age (64 vs. 58; p = 0.001) and fewer males (49% vs. 36%; p = 0.001). In multivariate analysis, factors that independently increased 6-month readmission risk were age ≥ 60 years (hazard ratio [HR]: 1.7, 95% CI: 1.4-2.2), females (HR: 2.2, 95% CI: 1.6-2.7), and congestive heart failure (CCF) (HR: 2.1, 95% CI: 1.4-2.6). Most cardiac readmissions (76%) happened during the first 60 days following index discharge.

CONCLUSION

Almost half the patients were readmitted within 6 months after an index admission for AF. Females, CCF, and advancing age were independently associated with an increased risk of 6-month readmission.

摘要

背景

心房颤动（AF）是全球最常见的心律失常。然而，关于发展中世界AF首次入院后再入院的数据描述并不充分。本研究评估了叙利亚AF首次入院后6个月再入院的发生率、预测因素和趋势。

方法

我们纳入了2021年7月至2023年11月期间因AF首次入住拉塔基亚三级中心的成年患者。患者在首次出院后接受6个月的再入院监测。数据取自患者的病历。

结果

共有649例患者纳入最终分析，其中320例（49%）在首次入院后6个月内再次入院。心脏原因是76%患者再入院的最常见原因，其中70%为AF。再入院患者的年龄中位数较高（64岁对58岁；p = 0.001），男性较少（49%对36%；p = 0.001）。在多变量分析中，独立增加6个月再入院风险的因素为年龄≥60岁（风险比[HR]：1.7，95%置信区间[CI]：1.4 - 2.2）、女性（HR：2.2，95% CI：1.6 - 2.7）和充血性心力衰竭（CCF）（HR：2.1，95% CI：1.4 - 2.6）。大多数心脏再入院（76%）发生在首次出院后的前60天内。