B型主动脉夹层假腔血栓形成的影响因素:一项单中心回顾性研究。

Influencing factors of false lumen thrombosis in type B aortic dissection: A single-center retrospective study.

作者信息

Tang Qian-Hui, Yang Han, Qin Zhong, Lin Qiu-Ning, Hu Ming, Qin Xiao, Chen Jing

机构信息

Department of Vascular and Endovascular Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.

出版信息

Open Med (Wars). 2025 May 7;20(1):20251179. doi: 10.1515/med-2025-1179. eCollection 2025.

Abstract

OBJECTIVES

To evaluate the factors associated with false lumen thrombosis in preoperative type B aortic dissection (TBAD) patients.

METHODS

Between January 2008 and December 2017, TBAD patients were evaluated. Participants were divided into patent, partial thrombosis, and complete thrombosis groups according to the status of the false lumen. Univariate analysis and logistic regression analysis were used to identify the factors associated with false lumen thrombosis.

RESULTS

A total of 285 participants fulfilled our inclusion criteria. Patients in the complete thrombosis group were significantly older than those in the partial thrombosis and patent groups (59 ± 10 vs 53 ± 11 and 50 ± 11 years, respectively), and combined shorter dissection lengths (290 ± 101 vs 354 ± 92 and 351 ± 102 mm, respectively). The following factors were associated with partial thrombosis of the false lumen with an odds ratio (OR) <1: primary tear size (OR, 0.96; 95% confidence interval [CI], 0.93-0.99; = 0.03), last tear size (OR, 0.93; 95% CI, 0.87-0.99; = 0.04), and the total number of tears (OR, 0.87; 95% CI, 0.78-0.98; = 0.02).

CONCLUSIONS

TBAD patients older than 59 years or with aortic dissection lengths of less than 290 mm were more likely to have a thrombosed false lumen.

摘要

目的

评估术前B型主动脉夹层(TBAD)患者假腔血栓形成的相关因素。

方法

对2008年1月至2017年12月期间的TBAD患者进行评估。根据假腔状态将参与者分为通畅组、部分血栓形成组和完全血栓形成组。采用单因素分析和逻辑回归分析来确定与假腔血栓形成相关的因素。

结果

共有285名参与者符合纳入标准。完全血栓形成组患者的年龄显著大于部分血栓形成组和通畅组患者(分别为59±10岁、53±11岁和50±11岁),且夹层长度较短(分别为290±101mm、354±92mm和351±102mm)。以下因素与假腔部分血栓形成相关,比值比(OR)<1:原发破口大小(OR,0.96;95%置信区间[CI],0.93-0.99;P=0.03)、末次破口大小(OR,0.93;95%CI,0.87-0.99;P=0.04)和破口总数(OR,0.87;95%CI,0.78-0.98;P=0.02)。

结论

年龄大于59岁或主动脉夹层长度小于290mm的TBAD患者假腔更易形成血栓。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ec1/12086627/09447fdb5c48/j_med-2025-1179-fig001.jpg

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