精准医学中的医学大数据存储:一项系统综述。

Medical Big Data Storage in Precision Medicine: A Systematic Review.

作者信息

Langarizadeh Mostafa, Hajebrahimi Mehdi

机构信息

Department of Health Information Management, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran.

出版信息

J Biomed Phys Eng. 2025 Jun 1;15(3):205-220. doi: 10.31661/jbpe.v0i0.2402-1730. eCollection 2025 Jun.

Abstract

BACKGROUND

The characteristics of medical data in Precision Medicine (PM), the challenges related to their storage and retrieval, and the effective facilities to address these challenges are importantly considered in implementing PM. For this purpose, a secured and scalable infrastructure for various data integration and storage is needed.

OBJECTIVE

This study aimed to determine the characteristics of PM data and recognize the challenges and solutions related to appropriate infrastructure for data storage and its related issues.

MATERIAL AND METHODS

In this systematic study, coherent research was conducted on Web of Science, Scopus, PubMed, Embase, and Google Scholar from 2015 to 2023. A total of 16 articles were selected and evaluated based on the inclusion and exclusion criteria and the central search theme of the study.

RESULTS

A total of 1,961 studies were identified from designated databases, 16 articles met the eligibility criteria and were classified into five main sections PM data and its major characteristics based on the volume, variety and velocity (3Vs) of medical big data, data quality issues, appropriate infrastructure for PM data storage, cloud computing and PM infrastructure, and security and privacy. The variety of PM data is categorized into four major categories.

CONCLUSION

A suitable infrastructure for precision medicine should be capable of integrating and storing heterogeneous data from diverse departments and sources. By leveraging big data management experiences from other industries and aligning their characteristics with those in precision medicine, it is possible to facilitate the implementation of precision medicine while avoiding duplication.

摘要

背景

精准医学(PM)中医疗数据的特征、与数据存储和检索相关的挑战以及应对这些挑战的有效设施在实施精准医学时都被重点考虑。为此,需要一个安全且可扩展的基础设施来进行各种数据集成和存储。

目的

本研究旨在确定精准医学数据的特征,并识别与数据存储的适当基础设施及其相关问题相关的挑战和解决方案。

材料与方法

在这项系统性研究中,于2015年至2023年在科学网、Scopus、PubMed、Embase和谷歌学术上进行了连贯的研究。根据纳入和排除标准以及研究的核心搜索主题,共筛选并评估了16篇文章。

结果

从指定数据库中总共识别出1961项研究,16篇文章符合纳入标准,并基于医疗大数据的体量、多样性和速度(3V)、数据质量问题、精准医学数据存储的适当基础设施、云计算与精准医学基础设施以及安全性和隐私性分为五个主要部分。精准医学数据的多样性分为四大类。

结论

精准医学的合适基础设施应能够集成和存储来自不同部门和来源的异构数据。通过借鉴其他行业的大数据管理经验,并使其特征与精准医学中的特征相匹配,有可能在避免重复的同时促进精准医学的实施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1856/12153493/9e6c02908d87/JBPE-15-205-g001.jpg

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