Schram Samantha J, Lillis Jason
Department of Psychological Sciences, University of Connecticut, 406 Babbidge Rd, Unit 1020, Storrs, CT 06269, USA.
Weight Control and Diabetes Research Center, 196 Richmond St, Providence, RI 02903, USA.
Behav Sci (Basel). 2025 Jun 7;15(6):788. doi: 10.3390/bs15060788.
A significant portion of individuals with overweight or obesity seek behavioral weight loss, which aims to modify behaviors and habits related to diet, physical activity, and lifestyle and has been shown to result in clinically meaningful weight loss and improved cardiometabolic health. While the physical outcomes of behavioral weight loss are well documented, relevant psychological processes and mental health outcomes are less studied. This secondary analysis examined psychological flexibility in relation to depression change and weight change in adults (N = 508) with a body mass index greater than 25 enrolled in a 3-month automated behavioral weight loss intervention. Psychological flexibility was assessed using the Comprehensive Assessment of Acceptance and Commitment Therapy Processes (CompACT), a tool based on Acceptance and Commitment Therapy (ACT) principles. The Patient-Reported Outcomes Measurement Information System (PROMIS) initiative Depression-Short Form, which collects information directly reported by patients, was used to measure levels of depression. Change in psychological flexibility was found to significantly moderate the positive relationship between weight change and change in depression over the course of a 3-month behavioral weight loss intervention, such that individuals with greater increases in psychological flexibility experienced greater reductions in depression levels when also losing weight. These results suggest that psychological flexibility may enhance the psychological benefits of behavioral weight loss and could be a useful target in a modified version of behavioral weight loss intervention.
很大一部分超重或肥胖的人寻求行为减肥，其目的是改变与饮食、身体活动和生活方式相关的行为和习惯，并且已被证明能带来具有临床意义的体重减轻和改善心脏代谢健康。虽然行为减肥的身体效果已有充分记录，但相关的心理过程和心理健康结果却较少被研究。这项二次分析考察了心理灵活性与体重指数大于25的成年人（N = 508）在接受为期3个月的自动行为减肥干预后的抑郁变化和体重变化之间的关系。心理灵活性使用基于接受与承诺疗法（ACT）原则的工具——接受与承诺疗法过程综合评估（CompACT）进行评估。患者报告结果测量信息系统（PROMIS）的抑郁简表，即直接收集患者报告信息的工具，被用于测量抑郁水平。研究发现，在为期3个月的行为减肥干预过程中，心理灵活性的变化显著调节了体重变化与抑郁变化之间的正向关系，即心理灵活性增加幅度更大的个体在体重减轻的同时，抑郁水平下降幅度更大。这些结果表明，心理灵活性可能会增强行为减肥的心理益处，并且可能是行为减肥干预改良版中的一个有用靶点。
