关于肾上腺素诱导脂质微团中脂肪分解机制的进一步研究。
Further studies on the mechanism of adrenaline-induced lipolysis in lipid micelles.
作者信息
Saito Y, Matsuoka N, Okuda H, Fujii S
出版信息
J Biochem. 1976 Nov;80(5):929-34. doi: 10.1093/oxfordjournals.jbchem.a131379.
Lipase [EC 3.1.1.3] depleted lipid micelles, in which lipolysis was not elicited by adrenaline, were prepared from lipid micelles. When these lipase-depleted lipid micelles incubated with adipose tissue extract containing lipase activity, adrenaline-induced lipolysis was restored to almost the same level as that of native lipid micelles. Adrenaline-induced lipolysis was not restored when the lipase-depleted lipid micelles were homogenized or sonicated. Various tissue extracts from kidney, lung, liver, and pancreas, and post-heparin plasma, which contained lipase activity, restored adrenaline-induced lipolysis in lipase-depleted lipid micelles.
从脂质微团制备了脂肪酶[EC 3.1.1.3]耗尽的脂质微团，其中肾上腺素不会引发脂解作用。当这些脂肪酶耗尽的脂质微团与含有脂肪酶活性的脂肪组织提取物一起孵育时，肾上腺素诱导的脂解作用恢复到与天然脂质微团几乎相同的水平。当脂肪酶耗尽的脂质微团被匀浆或超声处理时，肾上腺素诱导的脂解作用不会恢复。来自肾脏、肺、肝脏和胰腺的各种组织提取物以及含有脂肪酶活性的肝素后血浆，可恢复脂肪酶耗尽的脂质微团中肾上腺素诱导的脂解作用。
Zotero 插件