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[质子泵抑制剂与H2受体拮抗剂在根除幽门螺杆菌三联疗法中的比较]

[Proton-pump inhibitors versus H2-receptor antagonists in triple therapy for Helicobacter pylori eradication].

作者信息

Kanayama S

机构信息

Department of Internal Medicine and Molecular Science, Graduate School of Medicine, Osaka University.

出版信息

Nihon Rinsho. 1999 Jan;57(1):153-6.

Abstract

Triple therapy with two antibiotics and acid-suppressing drugs is widely accepted for H. pylori eradication. Both H2-receptor antagonist and proton-pump inhibitor are reported to enhance the eradication rate when antibiotics are administered together. Comparative studies using H2-receptor antagonist or proton-pump inhibitor in triple therapy were reviewed. The efficacy of H. pylori eradication regimens with H2-receptor antagonist or proton-pump inhibitor with two antibiotics is not significantly different.

摘要

两种抗生素与抑酸药物的三联疗法被广泛用于根除幽门螺杆菌。据报道,在联合使用抗生素时,H2受体拮抗剂和质子泵抑制剂均可提高根除率。对在三联疗法中使用H2受体拮抗剂或质子泵抑制剂的比较研究进行了综述。使用H2受体拮抗剂或质子泵抑制剂与两种抗生素组成的幽门螺杆菌根除方案的疗效无显著差异。

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