al Harbi M
Surgical Department, Royal Commission Medical Center, Yambu.
East Afr Med J. 1998 Dec;75(12):703-7.
To evaluate the prescribing patterns of surgeons for pre-operative antimicrobial prophylaxis.
A retrospective study based on data obtained from case records of surgical patients admitted into the Department of Surgery.
Department of Surgery, Royal Commission Medical Center, Madinat Yambu Al-Sinayah.
The study population comprised of 888 surgical patients who received antibiotic therapy either for prophylaxis or treatment during the period 1st November 1992 and 28th February 1995.
A total of 888 surgical patients received antibiotics during the study period, 191 (21.5%) for prophylaxis while 697 (78.5%) were given antibiotics for therapy before and after surgery. Ceftriaxone was the most commonly used antibiotic for prophylaxis, followed by augmentin and cefotaxime, and these were frequently given in multiple doses, extending beyond 24 hours.
There was unwarranted and over use of prophylactic agents in at least 70% of the patients, with increased costs to the Hospital. Effective prophylaxis can be accomplished with a single dose of a cephalosporin, such as ceftriaxone, cefuroxime or cefazolin, for the common surgical procedures. It is recommended that better compliance with principles of surgical antimicrobial prophylaxis be implemented Prophylactic antibiotic audit measures should be carried out by the control committee. The development of guidelines and standing orders for antimicrobial prophylaxis should help to improve compliance.
评估外科医生术前抗菌药物预防用药的处方模式。
基于从外科收治的手术患者病历中获取的数据进行的回顾性研究。
延布·锡奈亚皇家委员会医疗中心外科。
研究人群包括1992年11月1日至1995年2月28日期间接受抗生素治疗（用于预防或治疗）的888例手术患者。
在研究期间，共有888例手术患者接受了抗生素治疗，其中191例（21.5%）用于预防，而697例（78.5%）在手术前后接受抗生素治疗。头孢曲松是预防用药中最常用的抗生素，其次是奥格门汀和头孢噻肟，这些药物经常多次给药，用药时间超过24小时。
至少70%的患者存在不必要的预防性药物过度使用情况，这增加了医院的成本。对于常见的外科手术，单剂量的头孢菌素（如头孢曲松、头孢呋辛或头孢唑林）即可实现有效的预防。建议更好地遵守外科抗菌药物预防原则。控制委员会应开展预防性抗生素审核措施。制定抗菌药物预防指南和常规医嘱应有助于提高依从性。
