Ertl A, Saringer W, Heimberger K, Kindl P
Department of Neurosurgery, University of Vienna, Austria.
Med Phys. 1999 Feb;26(2):166-70. doi: 10.1118/1.598499.
Our aim in this study was to distinguish quantitatively between the localization accuracy of a commercially available stereotactic fixation device as claimed by the manufacturer and the target accuracy as measured by a user, applying neuroradiologic imaging in Gamma Knife planning and phantom irradiation. Missing the target is the most serious possible failure in Gamma Knife and Linac therapy. To reduce this risk, we developed a quality control algorithm and designed a phantom. To evaluate the accuracy of the targeting procedure with a Leksell Gamma unit, and to experience the possible errors in all procedural steps, irradiations of phantoms were performed, using the so-called "unknown" targeting method. Accuracy is defined by the extent of spatial deviation of the irradiated target from the calculated target. Digital imaging was used for therapy planning. GafChromic films, which had been irradiated while affixed to a specially developed phantom, were used for measuring the precision of the radiation unit. A series of MR images (in two plains: transverse and coronal) was acquired sequentially to image the three-dimensional (3-D) volume of the phantom. The results obtained for isocentric accuracy of the Leksell Gamma unit, model B, were in good agreement to the calculated position. The observed spatial deviations between calculated and irradiated targets is less than 1 mm. The newly designed phantom and quality control algorithm are useful in quality assurance measurements of stereotactic radiation therapy.
本研究的目的是,在伽玛刀治疗计划和体模照射中应用神经放射成像技术,定量区分制造商声称的市售立体定向固定装置的定位精度与使用者测量的靶点精度。在伽玛刀和直线加速器治疗中,错过靶点是最严重的可能失败情况。为降低这种风险,我们开发了一种质量控制算法并设计了一个体模。为评估使用Leksell伽玛装置进行靶向操作的准确性,并体验所有操作步骤中可能出现的误差,采用所谓的“未知”靶向方法对体模进行照射。准确性由照射靶点与计算靶点的空间偏差程度来定义。数字成像用于治疗计划。将贴附在专门开发的体模上进行照射的GafChromic胶片用于测量放射单元的精度。依次采集一系列磁共振图像(在两个平面:横断面和冠状面)以成像体模的三维(3-D)体积。型号为B的Leksell伽玛装置的等中心精度测量结果与计算位置高度吻合。计算靶点与照射靶点之间观察到的空间偏差小于1毫米。新设计的体模和质量控制算法在立体定向放射治疗的质量保证测量中很有用。