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[微骨折技术在膝关节全层软骨缺损治疗中的应用]

[The microfracture technic in the management of complete cartilage defects in the knee joint].

作者信息

Steadman J R, Rodkey W G, Briggs K K, Rodrigo J J

机构信息

Steadman Hawkins Clinic, Vail, Colorado, USA.

出版信息

Orthopade. 1999 Jan;28(1):26-32. doi: 10.1007/s001320050318.

Abstract

Full thickness defects of the articular cartilage rarely heal spontaneously. While some patients do not develop clinically significant problems from chondral defects, most eventually develop degenerative changes associated with the cartilage damage over time. Techniques to treat chondral defects include abrasion, drilling, tissue autografts, allografts, and cell transplantation. The senior author has developed a procedure referred to as the "microfracture." This technique enhances chondral resurfacing by providing a suitable environment for tissue regeneration and by taking advantage of the body's own healing potential. This technique has now been used in more than 1400 patients. Specially designed awls are used to make multiple perforations, or "microfractures", into the subchondral bone plate. The perforations are made as close together as necessary, but not so close that one breaks into another. Consequently, the microfracture holes are approximately three to four millimeters apart (or 3 to 4 holes per square centimeter). Importantly, the integrity of the subchondral bone plate is maintained. The released marrow elements form a "super clot" which provides an enriched environment for tissue regeneration. Follow up with long term results of more than 8 years have been positive and very encouraging.

摘要

关节软骨的全层缺损很少能自发愈合。虽然一些患者并未因软骨缺损而出现具有临床意义的问题,但大多数患者最终会随着时间的推移出现与软骨损伤相关的退行性改变。治疗软骨缺损的技术包括磨削、钻孔、组织自体移植、异体移植和细胞移植。资深作者开发了一种称为“微骨折”的手术方法。该技术通过为组织再生提供合适的环境并利用人体自身的愈合潜力来增强软骨表面修复。这项技术现已应用于1400多名患者。使用专门设计的锥子在软骨下骨板上制造多个穿孔,即“微骨折”。穿孔尽可能紧密排列,但不能过于紧密以至于相互连通。因此,微骨折孔之间的间距约为3至4毫米(或每平方厘米3至4个孔)。重要的是,软骨下骨板的完整性得以保持。释放出的骨髓成分形成一个“超级凝块”,为组织再生提供了丰富的环境。超过8年的长期随访结果是积极且非常令人鼓舞的。

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