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Progress report: the Arizona phase III study of the effect of wheat bran fiber on recurrence of adenomatous colon polyps.

作者信息

Earnest D L, Sampliner R E, Roe D J, van Leeuwen B, Guillen J, Reid M, Martinez M E, Marshall J R, Alberts D S

机构信息

Department of Medicine, University of Arizona Health Sciences Center, and the VA Medical Center, Tucson 85724-5028, USA.

出版信息

Am J Med. 1999 Jan 25;106(1A):43S-45S. doi: 10.1016/s0002-9343(99)00003-0.

Abstract

A double-blind, placebo-controlled Phase III cancer prevention trial in subjects with previous resection of adenomatous colon polyps is nearing completion. The study's primary objective is to evaluate the effects of daily dietary supplementation with large (13.5 g/day) versus small (2.0 g/day) doses of wheat bran fiber for 3 years. A summary of the study design and a progress report are presented.

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