Earnest D L, Sampliner R E, Roe D J, van Leeuwen B, Guillen J, Reid M, Martinez M E, Marshall J R, Alberts D S
Department of Medicine, University of Arizona Health Sciences Center, and the VA Medical Center, Tucson 85724-5028, USA.
Am J Med. 1999 Jan 25;106(1A):43S-45S. doi: 10.1016/s0002-9343(99)00003-0.
A double-blind, placebo-controlled Phase III cancer prevention trial in subjects with previous resection of adenomatous colon polyps is nearing completion. The study's primary objective is to evaluate the effects of daily dietary supplementation with large (13.5 g/day) versus small (2.0 g/day) doses of wheat bran fiber for 3 years. A summary of the study design and a progress report are presented.