Improving drug usage evaluation with microcomputer database software.

The use of microcomputer database software can help overcome many of the potential weaknesses of criteria-based drug usage evaluation (DUE) through the collection and assessment of drug use statistics on a broad basis. By allowing for more systematic and comprehensive data analyses, database software can target the selection of the most appropriate DUE topics; improve the accuracy, efficiency, and acceptance of DUE reports; and enhance the overall therapeutic- and cost-effectiveness of drug use in the institutional setting. The development of antibiotic use statistics in the area of surgical prophylaxis is presented as an example, with recommendations for similar applications in other therapeutic areas.