Edhag O, Swahn A
Acta Med Scand. 1976;200(6):457-63.
This paper reports the results of a retrospective study carried out with special reference to the survival rate in a series of 101 selected cases including patients with complete heart block (CHB) combined or not combined with Adams-Stokes attacks and patients with arrhythmic syncope without ECG evidence of CHB. All these patients were treated in our Department during 1958-68, none being artificially paced. Twenty-seven patients were alive at the end of the follow-up, i,e 6-15 years after admission to this Department on account of syncopal episodes or CHB. The survival rate--higher in females than males--was lower in the cases of CHB combined with Adams-Stokes attacks than in the cases of asymptomatic CHB. This applied also to the instances in which a complicating disease such as ischaemic heart disease (IHD), hypertension, diabetes, digitalis intoxication or cardiac enlargement coexisted. The survival rate in the 68 cases of CHB was higher at one year (68%) as well as at 5 years (37%) than that reported by other investigators. When assessing the survival rate in cases treated with artificial pacemakers, it is important to study the individual case histories with special reference to a previous or coexisting condition such as IHD, hypertension, diabetes or the presence of cardiac enlargement. The present results support the view that the indications for treatment with artificial pacing should be wide, albeit that the prognosis in this series was more favourable than might have been anticipated from observations by others.
本文报告了一项回顾性研究的结果,该研究特别参考了101例选定病例的生存率,这些病例包括合并或未合并阿-斯综合征的完全性心脏传导阻滞(CHB)患者以及无CHB心电图证据的心律失常性晕厥患者。所有这些患者在1958年至1968年期间在我们科室接受治疗,均未接受人工起搏治疗。随访结束时,即因晕厥发作或CHB入院6至15年后,有27例患者存活。生存率——女性高于男性——合并阿-斯综合征的CHB病例低于无症状CHB病例。这也适用于合并缺血性心脏病(IHD)、高血压、糖尿病、洋地黄中毒或心脏扩大等并发疾病的情况。68例CHB患者1年(68%)和5年(37%)的生存率高于其他研究者报告的生存率。在评估接受人工起搏器治疗病例的生存率时,特别参考既往或并存疾病如IHD、高血压、糖尿病或心脏扩大情况来研究个体病史很重要。目前的结果支持这样一种观点,即人工起搏治疗的适应证应该广泛,尽管该系列的预后比其他人的观察结果可能预期的更有利。