螺内酯的抗雄激素作用：不同作用机制（作者译）
[Antiandrogenic effect of spirolactones: different mechanisms of action (author's transl)].
作者信息
Mahoudeau J A, Corvol P, Valcke J C, Menard J, Bricaire H
出版信息
Ann Endocrinol (Paris). 1976 Jan-Feb;37(1):57-8.
PMID:1015793
Abstract
The spirolactones decrease the plasma testosterone levels in men. They also inhibit the specific dihydrotestosterone binding to rat prostate, and have no effect on 5 alpha-reductase. The spirolactones are antiandrogenic drugs, acting at several levels.
摘要
螺内酯可降低男性体内的血浆睾酮水平。它们还能抑制二氢睾酮与大鼠前列腺的特异性结合，且对5α-还原酶无作用。螺内酯是抗雄激素药物，作用于多个层面。
Zotero 插件