Bosova N N
Biull Eksp Biol Med. 1976;82(11):1377-9.
Whole gastrocnemius muscles, preliminarily (one month before) denervated, were auto- and homotransplanted in dogs. The transplanted muscles took at the site of transplantation; some of the transplanted material was lost and was resorbed; myoblasts were released from the viable disintegrating material. The muscle organ was built anew as a result of further differentiation of myogenic elements in the autotransplants under conditions of timely restoration of the circulation and innervation. No stable take of the transplant occurred in the case of homoplasty--the newlyformed muscle was lost as a result of the incompatibility reaction. Thus, preliminary denervation serves as an effective means of preparation of the muscle tissue for the autotransplantation.