Kazimierczak J
Bull Assoc Anat (Nancy). 1976 Mar;60(168):137-43.
The kidneys of 2 to 10 days old albino rats were fixed by perfusion and examined by transmission and scanning electron microscopy. Furthermore, vascular casts of renal vessels in rats of the same ages were effectuated by injection of methacrylate into the aorta and observed by SEM. The observation of glomerulogenesis in different stages has indicated that the glomerular capillaries originate in the interstitial vessels which penetrate into the cleft formed in the wall of the renal vesicle. Initially the capillaries have an aspect of small sinusoids which then expand peripherally and undergo successive subdivisions: the anastomosis in each glomerular lobule persists. The podocytes originate from the cells of the renal vesicle facing the penetrating capillaries. The initially primitive cells branch off successively and extend around the expanding capillaries with their small processes -- the foot processes which interdigitate with the corresponding structures of the neighbour cells.
对2至10日龄白化大鼠的肾脏进行灌注固定,并通过透射电子显微镜和扫描电子显微镜进行检查。此外,通过将甲基丙烯酸酯注入主动脉来制作相同年龄大鼠肾血管的血管铸型,并通过扫描电子显微镜进行观察。对不同阶段肾小球发生的观察表明,肾小球毛细血管起源于穿透肾小囊壁形成的裂隙的间质血管。最初,毛细血管呈小血窦样,然后向周边扩展并进行连续分支:每个肾小球小叶内的吻合持续存在。足细胞起源于肾小囊面对穿透性毛细血管的细胞。最初的原始细胞相继分支,并通过其小突起——足突围绕扩张的毛细血管延伸,足突与相邻细胞的相应结构相互交错。