Mantas J P, Bloebaum R D, Hofmann A A
Bone & Joint Research Lab, VA Medical Center, Salt Lake City, UT 84148.
J Appl Biomater. 1992 Fall;3(3):183-90. doi: 10.1002/jab.770030304.
An expanded polytetrafluoroethylene (PTFE) prosthesis used to reconstruct the posterior cruciate ligament in a 37-year-old Caucasian male was retrieved and histologically examined in this study. Backscattered electron (BSE) microscopy, utilized to observe the mineralized tissue ingrowth into the retrieved specimen, revealed an absence of bony ingrowth within the graft. Light microscopy demonstrated an exuberant foreign body giant cell response surrounding and invading the substance of the graft, and also revealed evidence of graft degradation. These observations indicate that PTFE may not be as favorable a material for reconstruction of ligamentous tissues as previously reported.
本研究中,取出了一名37岁白人男性用于重建后交叉韧带的膨体聚四氟乙烯(PTFE)假体,并进行了组织学检查。利用背散射电子(BSE)显微镜观察取出标本中矿化组织的向内生长情况,结果显示移植物内无骨向内生长。光学显微镜显示,移植物周围和内部有大量异物巨细胞反应,同时也有移植物降解的迹象。这些观察结果表明,PTFE作为重建韧带组织的材料可能并不像先前报道的那样理想。