Kremmydas G P, Bezerianos A, Bountis T
Department of Medical Physics, Medical School, University of Patras, Greece.
Stud Health Technol Inform. 1997;43 Pt B:576-80.
Spiral waves are though to be the underlying mechanism of re-entrant ventricular and atrial tachycardias. In such cases, one is generally interested in eliminating spiral wave activity from the medium. In this paper, solve a cubic FitzHugh-Nagumo system of PDEs is solved in two dimensions with initial conditions such that a spiral wave is formed at the center of a rectangular grid. Then the effect of a spatially-localized step-like periodic forcing placed at different positions around the spiral tip is studied. Due to this forcing, the tip begins to drift away from the perturbation in a direction that depends on their relative location. By shifting successively the location of the perturbation relative to that of the tip strategy is developed which it is possible to pursuit the spiral wave away from the center of the grid accelerating its drift with every shift of the perturbation.
螺旋波被认为是折返性室性和房性心动过速的潜在机制。在这种情况下,人们通常感兴趣的是消除介质中的螺旋波活动。在本文中,求解了二维的立方FitzHugh-Nagumo偏微分方程组,其初始条件使得在矩形网格的中心形成一个螺旋波。然后研究了在螺旋波尖端周围不同位置施加的空间局部化阶梯状周期强迫的影响。由于这种强迫,尖端开始朝着取决于它们相对位置的方向远离扰动漂移。通过相对于尖端连续移动扰动的位置,开发了一种策略,通过每次移动扰动,可以将螺旋波从网格中心驱离,加速其漂移。