Taylor S M, Langan E M, Snyder B A, Cull D L, Crane M M
Department of Surgical Education, Greenville Hospital System, South Carolina 29605, USA.
Am Surg. 1999 Apr;65(4):323-7.
Although the efficacy of carotid endarterectomy has been well established, nonendarterectomy procedures of the carotid bifurcation have only sporadically been reported. Of 334 consecutive nontraumatic carotid procedures performed on 321 patients from July 1992 until May 1997, 306 (91.6%) were carotid endarterectomies, 14 (4.2%) were carotid-subclavian bypasses/transpositions, and 14 (4.2%) were nonendarterectomy procedures of the carotid artery. These latter 14 cases (nine females and five males; mean age, 63 years) were all symptomatic (neurological or painful mass) and included carotid kink/coil resection (n = 3; 0.9%), endarterectomy and vertebral transposition (n = 2; 0.6%), carotid aneurysm resection (n = 2; 0.6%), carotid body tumor resection (n = 2; 0.6%), carotid stump ligation/external endarterectomy (n = 1; 0.3%), infected/bleeding carotid patch removal with vein graft replacement (n = 1; 0.3%), saphenous vein graft replacement (n = 1; 0.3%), carotid dilatation for fibromuscular dysplasia (n = 1; 0.3%), and descending aorta to carotid bypass (n = 1; 0.3%). With 30 day follow-up complete for all 334 carotid operations, 10 perioperative strokes (2.9%) and five deaths (1.5%) occurred for a combined stroke/death rate of 3.3 per cent. Of the 14 nonendarterectomy carotid artery operations, there were no strokes or deaths; with mean follow-up of 13 months, 13 patients (92.9%) are asymptomatic, patent, and disease-free. Three severe transient cranial nerve (CN) neuropraxias (21.4%), one myocardial infarction (7.1%), and one late death (mesenteric ischemia at 2 months), however, occurred. Although no statistical differences in stroke, death, and stroke/death occurred between the endarterectomy versus the nonendarterectomy group, transient CN injury was more common in the nonendarterectomy group (21.4% versus 4.1%; P = 0.027). Although nonendarterectomy procedures of the carotid bifurcation are infrequently needed, they seem safe, effective, and indicated in selected patients, despite a higher incidence of transient CN injury.
尽管颈动脉内膜切除术的疗效已得到充分证实,但关于颈动脉分叉处的非内膜切除术的报道却很零散。在1992年7月至1997年5月期间对321例患者进行的334例连续性非创伤性颈动脉手术中,306例(91.6%)为颈动脉内膜切除术,14例(4.2%)为颈动脉-锁骨下动脉旁路移植术/转位术,14例(4.2%)为颈动脉非内膜切除术。后14例患者(9例女性和5例男性;平均年龄63岁)均有症状(神经症状或疼痛性肿块),包括颈动脉扭结/盘曲切除术(n = 3;0.9%)、内膜切除术和椎动脉转位术(n = 2;0.6%)、颈动脉动脉瘤切除术(n = 2;0.6%)、颈动脉体瘤切除术(n = 2;0.6%)、颈动脉残端结扎/外膜切除术(n = 1;0.3%)、感染/出血性颈动脉补片切除并静脉移植置换术(n = 1;0.3%)、大隐静脉移植置换术(n = 1;0.3%)、纤维肌性发育异常的颈动脉扩张术(n = 1;0.3%)以及降主动脉至颈动脉旁路移植术(n = 1;0.3%)。对所有334例颈动脉手术进行了30天的随访,围手术期发生10例卒中(2.9%)和5例死亡(1.5%),卒中/死亡率合计为3.3%。在14例颈动脉非内膜切除术中,无卒中或死亡发生;平均随访13个月,13例患者(92.9%)无症状、血管通畅且无疾病。然而,发生了3例严重的短暂性脑神经(CN)神经失用症(21.4%)、1例心肌梗死(7.1%)和1例晚期死亡(2个月时肠系膜缺血)。尽管内膜切除术组与非内膜切除术组在卒中、死亡及卒中/死亡方面无统计学差异,但短暂性CN损伤在非内膜切除术组更为常见(21.4%对4.1%;P = 0.027)。尽管颈动脉分叉处的非内膜切除术很少需要,但尽管短暂性CN损伤发生率较高,但它们似乎是安全、有效的,且适用于特定患者。