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因耶尔森菌病导致的纯合子β地中海贫血患者发生急性呼吸窘迫综合征。

ARDS in a patient with homozygous beta-thalassemia due to yersiniosis.

作者信息

Mavrommati P, Ladis V, Lagona E, Giannaki M, Raftopoulou A, Hatzis T

机构信息

Critical Care Department, Aghia Sophia Children's Hospital, Athens, Greece.

出版信息

Intensive Care Med. 1999 Feb;25(2):226-9. doi: 10.1007/s001340050822.

DOI:10.1007/s001340050822
PMID:10193554
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7095203/
Abstract

We report a case of Yersinia enterocolitica sepsis syndrome and the acute respiratory distress syndrome in a chronically transfused adolescent with beta-thalassemia. This manifestation of serious Y. enterocolitica infection has not previously been reported. Dyspnea, hypoxia, and fever were the principal features of the clinical presentation. The acute onset of respiratory symptoms occurred after appendectomy. Chest radiographs revealed frontal bilateral infiltrates and alveolar consolidation to three quadrants. Y. enterocolitica was identified from blood and intraoperative appendix cultures. Although there was no need for mechanical ventilation, a remarkable persistence of clinical and X-ray findings was noted. Therapy with high levels of oxygen, and intravenous amikacin and piperacillin/tazobactam led to a favorable outcome.

摘要

我们报告了一例患有β地中海贫血且长期输血的青少年发生小肠结肠炎耶尔森菌败血症综合征及急性呼吸窘迫综合征的病例。小肠结肠炎耶尔森菌严重感染的这种表现此前未见报道。呼吸困难、低氧血症和发热是临床表现的主要特征。呼吸道症状急性发作于阑尾切除术后。胸部X线片显示双侧额叶浸润及三个象限的肺泡实变。从血液和术中阑尾培养物中鉴定出小肠结肠炎耶尔森菌。尽管无需机械通气,但临床和X线检查结果仍持续显著存在。高浓度吸氧、静脉注射阿米卡星和哌拉西林/他唑巴坦治疗取得了良好效果。

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Intensive Care Med. 1999 Feb;25(2):226-9. doi: 10.1007/s001340050822.
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