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[盖伦制剂差异的后果以及布地奈德和5-氨基水杨酸治疗克罗恩病的临床试验结果]

[Consequences of galenic differences and outcome of clinical trials with budesonide and 5-aminosalicylic acids for therapy of Crohn disease].

作者信息

Stange E F

机构信息

Bereich Gastroenterologie, Medizinische Klinik, Universität Lübeck.

出版信息

Med Klin (Munich). 1999 Feb 15;94 Suppl 1:39-41. doi: 10.1007/BF03042032.

Abstract

Budesonide in both galenic forms is suitable for the treatment of a flare of Crohn's disease of up to moderate activity. The same holds true for 5-amino-salicylates, although they are less effective. Topical steroids delay but do not prevent relapses. Aminosalicylates may be used in the postoperative situation for prevention of relapse but are not significantly effective after drug-induced remission.

摘要

两种剂型的布地奈德均适用于治疗中度及以下活动期的克罗恩病发作。5-氨基水杨酸类药物也是如此,尽管其效果较差。局部用类固醇可延迟但不能预防复发。氨基水杨酸类药物可用于术后预防复发,但在药物诱导缓解后效果不显著。

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