The facial artery musculomucosal (FAMM) flap is a newly designed buccal mucosal flap that was first described in 1992. The long rotational arc of this flap is particularly suitable for anterior palatal defects that are otherwise difficult to treat with local flaps. However, after the first clinical reports, some controversies arose about the reliability of this flap, so we conducted an anatomical study of the vascular pattern with a latex preparation in 10 cadavers. We studied the variations of the course of the facial artery and focused on the relationship between the facial artery and vein within the pedicle. We concluded that the flap is more an arterialized flap than an axial-pattern flap, and have given anatomical landmarks to optimize the survival rate. Our preliminary clinical results (five good results, one complete failure) are acceptable.