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鞘内注射速度对1%重比重布比卡因单侧脊髓阻滞的影响。一项随机双盲研究。

Effects of speed of intrathecal injection on unilateral spinal block by 1% hyperbaric bupivacaine. A randomized, double-blind study.

作者信息

Casati A, Fanelli G, Cappelleri G, Aldegheri G, Berti M, Senatore R, Torri G

机构信息

Department of Anesthesiology and Intensive Care, University of Milan, IRCCS H San Raffaele.

出版信息

Minerva Anestesiol. 1999 Jan-Feb;65(1-2):5-10.

Abstract

BACKGROUND

To evaluate if the speed of intrathecal injection affects the lateral distribution of spinal block during unilateral spinal anaesthesia with 1% hyperbaric bupivacaine.

DESIGN

prospective, randomized, double-blind study.

SETTING

anaesthesia Department at a University Hospital.

PATIENTS

30 ASA physical status I-II patients, scheduled for elective orthopedic surgery involving one lower limb only (ankle and foot surgery).

INTERVENTIONS

after placing the patients in the lateral decubitus position with the site to be operated on dependent, dural puncture was performed at L3-L4 interspace using a 25-Gauge Whitacre spinal needle. After the needle hole had been turned toward the dependent side, patients were randomized to receive 8 mg of 1% hyperbaric bupivacaine injected over either 40 sec (Group SLOW, n = 15) or 3 sec (Group FAST, n = 15). The lateral position was maintained for 15 min.

MEASUREMENTS

a blind observer evaluated the evolution of sensory (pinprick test) and motor (modified Bromage scale) blocks on both the dependent and nondependent sides until the regression of motor block by one degree.

RESULTS

No differences in the maximal sensory level on both the dependent and nondependent sides were observed in the two groups. Unilateral sensory block was onserved in 6 patients in group SLOW (40%) and in 5 patients in group FAST (33%), (p = not significant[NS]. Unilateral motor block was observed in 9 patients in group SLOW (60%) and in 10 patients in group FAST (66%) (NS).

CONCLUSIONS

Extremely reduced speeds of intrathecal injection did not improve the lateral distribution of spinal block when injecting 8 mg of 1% hyperbaric bupivacaine through a pencil-point directional spinal needle.

摘要

背景

评估在使用1%重比重布比卡因进行单侧脊髓麻醉时,鞘内注射速度是否会影响脊髓阻滞的侧向分布。

设计

前瞻性、随机、双盲研究。

地点

一所大学医院的麻醉科。

患者

30例美国麻醉医师协会(ASA)身体状况为I-II级的患者,计划进行仅涉及一侧下肢(踝关节和足部手术)的择期骨科手术。

干预措施

将患者置于患侧在下的侧卧位后,使用25G Whitacre脊髓穿刺针在L3-L4间隙进行硬膜穿刺。在针孔转向患侧后,患者被随机分为两组,分别接受8mg 1%重比重布比卡因,注射时间为40秒(慢注组,n = 15)或3秒(快注组,n = 15)。保持侧卧位15分钟。

测量指标

由一名盲法观察者评估患侧和非患侧感觉(针刺试验)和运动(改良Bromage评分)阻滞的进展情况,直至运动阻滞消退一级。

结果

两组患侧和非患侧的最大感觉平面均无差异。慢注组6例患者(40%)出现单侧感觉阻滞,快注组5例患者(33%)出现单侧感觉阻滞(p = 无统计学意义[NS])。慢注组9例患者(60%)出现单侧运动阻滞,快注组10例患者(66%)出现单侧运动阻滞(NS)。

结论

当通过笔尖式定向脊髓穿刺针注射8mg 1%重比重布比卡因时,极度减慢鞘内注射速度并不能改善脊髓阻滞的侧向分布。

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